resiniferatoxin

Known as: RTX diterpene, 6,7-deepoxy-6,7-didehydro-5-deoxy-21-dephenyl-21-(phenylmethyl)daphnetoxin 20-(3-hydroxy-5-methoxybenzeneacetate), reciniferatoxin 
A naturally occurring capsaicin analog found in the latex of the cactus Euphorbia resinifera with analgesic activity. Resiniferatoxin (RTX) binds to… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Patients with IgG4-related disease (IgG4-RD) typically have elevated serum concentrations of IgG4 and share histopathologic… (More)
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Highly Cited
2008
Highly Cited
2008
Several case reports suggest that rituximab (RTX) could be effective in steroid-dependent nephrotic syndrome, but RTX efficacy… (More)
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Highly Cited
2005
Highly Cited
2005
OBJECTIVES To study TRPV1 immunoreactivity in the urothelium of patients with neurogenic detrusor overactivity (NDO) before and… (More)
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Highly Cited
2004
Highly Cited
2004
Knowledge of the distribution and function of the vanilloid receptor (VR-1 or TRPV1) in the CNS lacks the detailed appreciation… (More)
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Highly Cited
2004
Highly Cited
2004
OBJECTIVE To compare PGP9.5 and transient receptor potential vanilloid receptor (TRPV1) suburothelial immunoreactivity between… (More)
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Review
2002
Review
2002
Thymidylate synthase (TS) is a key enzyme in the de novo synthesis of 2'-deoxythymidine-5'-monophosphate (dTMP) from 2… (More)
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Highly Cited
2002
Highly Cited
2002
OBJECTIVES To obtain evidence for dose response and to extend evidence of safety and efficacy for B lymphocyte depletion in… (More)
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Highly Cited
2001
Highly Cited
2001
The highly potent vanilloid receptor (VR) agonist resiniferatoxin has been radiolabeled with 125I, and the pharmacology to the… (More)
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Review
1999
Review
1999
PURPOSE Pharmacological treatment of the overactive bladder relies on partially blocking the efferent parasympathetic innervation… (More)
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Highly Cited
1989
Highly Cited
1989
Resiniferatoxin is an extremely irritant diterpene present in the latex of several members of the genus Euphorbia. Its mechanism… (More)
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