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recombinase activity

Catalysis of the identification and base-pairing of homologous sequences between single-stranded DNA and double-stranded DNA. [GOC:elh]
National Institutes of Health

Papers overview

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2012
2012
The BRC repeat is a structural motif in the tumor suppressor BRCA2 (breast cancer type 2 susceptibility protein), which promotes… Expand
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Highly Cited
2010
Highly Cited
2010
Homologous recombination mediated by RAD51 recombinase helps eliminate chromosomal lesions, such as DNA double-strand breaks… Expand
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2007
2007
FimB and FimE are site-specific recombinases, part of the lambda integrase family, and invert a 314 bp DNA switch that controls… Expand
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Highly Cited
2005
Highly Cited
2005
Common lymphoid progenitors (CLPs) are the first bone marrow precursors in which V(D)J recombinase activity is up-regulated. Here… Expand
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Highly Cited
2005
Highly Cited
2005
Recombinase proteins assembled into helical filaments on DNA are believed to be the catalytic core of homologous recombination… Expand
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Highly Cited
2004
Highly Cited
2004
Expression of V(D)J recombinase activity in developing lymphocytes is absolutely required for initiation of V(D)J recombination… Expand
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Highly Cited
1997
Highly Cited
1997
The process of V(D)J recombination is crucial for regulating the development of B cells and for determining their eventual… Expand
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Highly Cited
1996
Highly Cited
1996
A common V(D)J recombinase that recognizes a conserved recombination signal sequence (RSS) mediates the assembly of… Expand
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Highly Cited
1990
Highly Cited
1990
A fusion complementary DNA in the T cell line HSB-2 elucidates a provocative mechanism for the disruption of the putative… Expand
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1988
1988
Using retroviral recombination substrates, we investigated the developmental stage of expression of V(D)J recombinase activity… Expand
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