recombinase activity

Catalysis of the identification and base-pairing of homologous sequences between single-stranded DNA and double-stranded DNA. [GOC:elh]

Topic mentions per year

Topic mentions per year

1982-2017
051019822017

Papers overview

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Highly Cited
2006
Highly Cited
2006
Neural stem cells are known to give rise to distinct subtypes of neurons and glial cells over time by changing their competency… (More)
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Highly Cited
2004
Highly Cited
2004
Expression of V(D)J recombinase activity in developing lymphocytes is absolutely required for initiation of V(D)J recombination… (More)
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Highly Cited
2004
Highly Cited
2004
Oocyte-specific deletion of ovarian genes using Cre/loxP technology provides an excellent tool to understand their physiological… (More)
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Highly Cited
2001
Highly Cited
2001
The advent of conditional and tissue-specific recombination systems in gene-targeted or transgenic mice has permitted an… (More)
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Highly Cited
1999
Highly Cited
1999
Conditional DNA excision between two LoxP sites can be achieved in the mouse using Cre-ER(T), a fusion protein between a mutated… (More)
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Highly Cited
1997
Highly Cited
1997
The Cre/loxP site-specific recombination system derived from bacteriophage P1 provides a convenient tool for directed… (More)
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Highly Cited
1997
Highly Cited
1997
Reexpression of the V(D)J recombinase-activating genes RAG1 and RAG2 in germinal center B cells creates the potential for… (More)
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Highly Cited
1997
Highly Cited
1997
Repair of DNA damage resulting in double-strand breaks (DSBs) is controlled by gene products executing homologous recombination… (More)
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Highly Cited
1990
Highly Cited
1990
A fusion complementary DNA in the T cell line HSB-2 elucidates a provocative mechanism for the disruption of the putative… (More)
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Highly Cited
1989
Highly Cited
1989
The RAG-1 (recombination activating gene-1) genomic locus, which activates V(D)J recombination when introduced into NIH 3T3… (More)
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