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ras Oncogene

Known as: RAS Family Oncogene, Oncogene RAS, Ras oncogenes 
A family of oncogenes that are highly homologous with the retrovirus-associated DNA sequences (ras) originally isolated from Harvey and Kirsten… 
National Institutes of Health

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8 relations

Broader (1)

Genes, ras
Homo sapiensNeoplastic Cell TransformationRAB39B geneRAB40AL gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1988
Highly Cited
1988
A point mutation in the last intron responsible for increased expression and transforming activity of the c-Ha-ras oncogene
The T24/EJ allele of the Ha-ras proto-oncogene owes its powerful oncogenic activity not merely to the well documented mutation… 
Highly Cited
1988
Highly Cited
1988
Dexamethasone-dependent inhibition of differentiation of C2 myoblasts bearing steroid-inducible N-ras oncogenes
ras proteins are localized to the plasma membrane where they are postulated to interact with growth factor receptors and other… 
Highly Cited
1988
Highly Cited
1988
Relationship between an activated N-ras oncogene and chromosomal abnormality during leukemic progression from myelodysplastic syndrome.
The relationship between chromosomal abnormality and oncogene activation was investigated during leukemic progression in two… 
Review
1987
Review
1987
Activated neu oncogene sequences in primary tumors of the peripheral nervous system induced in rats by transplacental exposure to ethylnitrosourea.
Neurogenic tumors were selectively induced in high incidence in F344 rats by a single transplacental exposure to the direct… 
Highly Cited
1986
Highly Cited
1986
A human gastric carcinoma contains a single mutated and an amplified normal allele of the Ki-ras oncogene.
The DNA from various human tumors and tumor cell lines was screened for the presence of mutated ras oncogenes with synthetic… 
Highly Cited
1986
Highly Cited
1986
O6-methylguanine mutation and repair is nonuniform. Selection for DNA most interactive with O6-methylguanine.
Highly Cited
1986
Highly Cited
1986
Enhanced spontaneous metastasis of mouse carcinoma cells transfected with an activated c‐Ha‐ras‐1 gene
To investigate whether the presence of an activated ras oncogene influences the ability of tumour cells to metastasize, the c‐Ha… 
Highly Cited
1985
Highly Cited
1985
Yeast and mammalian ras proteins have conserved biochemical properties
Mammalian ras oncogenes encode polypeptides of relative molecular mass (Mr) 21,000 (p21) which bind GTP and GDP1,2. Oncogenic ras… 
Highly Cited
1984
Highly Cited
1984
Developmental regulation of a dictyostelium gene encoding a protein homologous to mammalian ras protein
Highly Cited
1983
Highly Cited
1983
Presence of a Kirsten murine sarcoma virus ras oncogene in cells transformed by 3-methylcholanthrene
Oncogenes have previously been reported in the DNAs of mouse fibroblast lines which had become transformed after in vitro… 
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