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ras Oncogene

Known as: RAS Family Oncogene, Oncogene RAS, Ras oncogenes 
A family of oncogenes that are highly homologous with the retrovirus-associated DNA sequences (ras) originally isolated from Harvey and Kirsten… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
RAS genes (HRAS, KRAS, and NRAS) comprise the most frequently mutated oncogene family in human cancer. With the highest RAS… Expand
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Highly Cited
2003
Highly Cited
2003
We have targeted a K-ras allele in mouse embryonic stem (ES) cells to express a K-Ras(V12) oncoprotein along with a marker… Expand
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Highly Cited
2001
Highly Cited
2001
About 30% of human tumours carry ras gene mutations. Of the three genes in this family (composed of K-ras, N-ras and H-ras), K… Expand
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Highly Cited
1995
Highly Cited
1995
The growth of solid tumors in vivo beyond 1-2 mm in diameter requires induction and maintenance of an angiogenic response. This… Expand
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Review
1993
Review
1993
We examined 82 surgically resected or biopsied, formalin-fixed, paraffin-embedded primary adenocarcinomas of the pancreas for the… Expand
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Highly Cited
1990
Highly Cited
1990
BACKGROUND The capability of activated oncogenes to induce malignant transformation of immortalized cells in vitro has suggested… Expand
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Highly Cited
1989
Highly Cited
1989
The crystal structure of the guanine-nucleotide-binding domain of p21 (amino acids 1–166) complexed to the guanosine triphosphate… Expand
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Highly Cited
1987
Highly Cited
1987
RNAse A mismatch cleavage analysis of 66 primary human colon tumours reveals a high incidence of K-ras genes with mutations at… Expand
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Highly Cited
1987
Highly Cited
1987
To define the role of cellular oncogenes in human cancers, we studied the prevalence of mutational activation of ras oncogenes in… Expand
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Highly Cited
1983
Highly Cited
1983
Transfection of embryo fibroblasts by a human ras oncogene does not convert them into tumour cells unless the fibroblasts are… Expand
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