ras Oncogene

Known as: RAS Family Oncogene, Oncogene RAS, Ras oncogenes 
A family of oncogenes that are highly homologous with the retrovirus-associated DNA sequences (ras) originally isolated from Harvey and Kirsten… (More)
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
Activating mutations in the ras oncogene are not considered sufficient to induce abnormal cellular proliferation in the absence… (More)
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Highly Cited
2003
Highly Cited
2003
We have targeted a K-ras allele in mouse embryonic stem (ES) cells to express a K-Ras(V12) oncoprotein along with a marker… (More)
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Highly Cited
2001
Highly Cited
2001
About 30% of human tumours carry ras gene mutations. Of the three genes in this family (composed of K-ras, N-ras and H-ras), K… (More)
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Highly Cited
2000
Highly Cited
2000
Gliomas are the most common primary malignant brain tumours and are classified into four clinical grades, with the most… (More)
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Highly Cited
1995
Highly Cited
1995
The growth of solid tumors in vivo beyond 1-2 mm in diameter requires induction and maintenance of an angiogenic response. This… (More)
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Review
1992
Review
1992
Activation of ras oncogenes is commonly found in human neoplasms. We have investigated 280 human lung cancer specimens for ras… (More)
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Highly Cited
1990
Highly Cited
1990
BACKGROUND The capability of activated oncogenes to induce malignant transformation of immortalized cells in vitro has suggested… (More)
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Highly Cited
1987
Highly Cited
1987
RNAse A mismatch cleavage analysis of 66 primary human colon tumours reveals a high incidence of K-ras genes with mutations at… (More)
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Highly Cited
1987
Highly Cited
1987
To define the role of cellular oncogenes in human cancers, we studied the prevalence of mutational activation of ras oncogenes in… (More)
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Highly Cited
1983
Highly Cited
1983
Transfection of embryo fibroblasts by a human ras oncogene does not convert them into tumour cells unless the fibroblasts are… (More)
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