rab GTP-Binding Proteins

Known as: GTPases, rab, GTP-Binding Proteins, rab, rab G Proteins 
A large family of MONOMERIC GTP-BINDING PROTEINS that play a key role in cellular secretory and endocytic pathways.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2016
0246819952016

Papers overview

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2015
2015
Mutations in the PTEN-induced kinase 1 (PINK1) are causative of autosomal recessive Parkinson's disease (PD). We have previously… (More)
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2014
2014
Membrane fusion in the endocytic pathway is mediated by a protein machinery consistent of Rab GTPases, tethering factors and… (More)
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2012
2012
Autophagosome formation is a complex cellular process, which requires major membrane rearrangements leading to the creation of a… (More)
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2012
2012
We recently generated rab-Gal4 lines for 25 of 29 predicted Drosophila rab GTPases. These lines provide tools for the expression… (More)
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2011
2011
Endocytic system dysfunction is one of the earliest disturbances that occur in Alzheimer's disease (AD), and may underlie the… (More)
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2008
2008
Exocytic events are tightly regulated cellular processes in which rab GTPases and their interacting proteins perform an important… (More)
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2005
2005
The organization and sorting of proteins within the Golgi stack to establish and maintain its cis to trans polarization remains… (More)
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2003
2003
Members of the golgin family of coiled-coil proteins have been implicated in the tethering of vesicles to Golgi membranes and… (More)
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Highly Cited
2000
Highly Cited
2000
Rab GTPases are recognized as critical regulatory factors involved in vesicular membrane transport and endosomal fusion. For… (More)
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1995
1995
Small GTPases of the rab family are involved in the regulation of vesicular transport. The restricted distribution of each of… (More)
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