quinomycin
National Institutes of Health
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Cancer stem cells (CSCs) appear to explain many aspects of the neoplastic evolution of tumors and likely account for enhanced…
Natural products display impressive activities against a wide range of targets, including viruses, microbes, and tumors. However…
Drugs from bugs . We have successfully expanded the scope of our E. coli-based total biosynthesis of natural products and their…
Streptomyces triostinicus produces triostin A, an antitumor antibiotic, as its major secondary metabolite. Surprisingly, this…
The quinomycin antibiotic UK-63052 (designated QN) exhibits a chemical structure related to the antibiotic echinomycin which is…
Quinaldopeptin, a new type of quinomycin antibiotic, was isolated from the culture of Streptoverticillium album strain Q132-6…
The interaction between UK63052, a novel derivative of the quinomycin group of bifunctional intercalating antibiotics, with DNA…
UK-63,052 complex, a new group of quinomycin-like antibiotics comprising UK-63,052 (factor A), UK-63,598 (factor C), UK-65,662…
Quinomycin C, triostin A and triostin C are peptide antibiotics of the quinoxaline family, of which echinomycin (quinomycin A) is…
The interaction with DNA of six chemically synthesized derivatives of the quinoxaline antibiotics was investigated. Five of the…