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quinolinate biosynthetic process

Known as: quinolinate anabolism, quinolinate formation, quinolinate biosynthesis 
The chemical reactions and pathways resulting in the formation of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic… Expand
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
The structure of tryptophan 2,3-dioxygenase (TDO) from Ralstonia metallidurans was determined at 2.4 A. TDO catalyzes the… Expand
Review
2006
Review
2006
Pyridine nucleotides are key redox carriers in the soluble phase of all living cells, and both NAD and NADP play crucial roles in… Expand
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1995
1995
Abstract: The metabolism of l‐tryptophan to the neuroactive kynurenine pathway metabolites, l‐kynurenine, kynurenate and… Expand
Review
1994
Review
1994
Publisher Summary Quinolinic acid is found throughout nature in organisms ranging from bacteria to humans. Chemically this… Expand
Highly Cited
1988
Highly Cited
1988
The two genes, nadA and nadB, responsible for quinolinate biosynthesis from aspartate and dihydroxyacetone phosphate in… Expand
1983
1983
Liver cells pre-incubated with 1 mM-DL-6-chlorotryptophan are less sensitive to tryptophan-mediated inhibition of gluconeogenesis… Expand
1981
1981
1. The metabolism of L-tryptophan by liver cells prepared from fed normal, adrenalectomized and streptozotocin-diabetic rats was… Expand
1978
1978
Evidence for the formation of an unstable intermediate in the synthesis of quinolinate from aspartate and dihydroxyacetone… Expand
1978
1978
Abstract Two proteins (A and B) from Escherichia coli are required for the synthesis of the NAD precursor quinolinate from… Expand
1977
1977
Dihydroxy [3-14C]acetone phosphate was prepared enzymatically from [1-14C]glucose and use as a substrate in a partially purified… Expand