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quinine 3-monooxygenase activity
Known as:
nifedipine oxidase activity
, quinine 3-hydroxylase activity
, quinine,NADPH:oxygen oxidoreductase activity
Catalysis of the reaction: H(+) + NADPH + O(2) + quinine = 3-hydroxyquinine + H(2)O + NADP(+). [EC:1.14.13.67, RHEA:20152]
National Institutes of Health
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2000
2000
A POTENT INHIBITOR OF BOTH P-GLYCOPROTEIN AND CYP 3 A IN VITRO
C. Wandel
,
R. Kim
,
F. Guengerich
,
A. Wood
2000
Corpus ID: 34786579
Mibefradil, a calcium Tand L-channel blocker developed for use in hypertension, was recently removed from the market after…
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