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pyruvate dehydrogenase (acetyl-transferring) kinase

Known as: (pyruvate dehydrogenase (lipoamide))kinase, PDH kinase, pyruvate dehydrogenase kinase 
 
National Institutes of Health

Papers overview

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2018
2018
A series of triple action Pt(iv) prodrugs was designed to test the hypothesis that multi-action compounds, where each bioactive… Expand
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Review
2014
Review
2014
  • In-kyu Lee
  • Diabetes & metabolism journal
  • 2014
  • Corpus ID: 17781593
The pyruvate dehydrogenase complex (PDC) is an emerging target for the treatment of metabolic syndrome. To maintain a steady… Expand
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Highly Cited
2013
Highly Cited
2013
Defining the metabolic programs that underlie stem cell maintenance will be essential for developing strategies to manipulate… Expand
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Highly Cited
2011
Highly Cited
2011
Dopaminergic (DA) neuron degeneration is a feature of brain aging but is markedly increased in patients with Parkinson’s disease… Expand
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2010
2010
Aging presumably initiates shifts in substrate oxidation mediated in part by changes in insulin sensitivity. Similar shifts occur… Expand
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2009
2009
Background Peroxisome proliferator-activated receptors (PPARs) are a family of three (PPARα, -β/δ, and -γ) nuclear receptors. In… Expand
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2008
2008
The heart adapts to changes in nutritional status and energy demands by adjusting its relative metabolism of carbohydrates and… Expand
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2008
2008
A characteristic manifestation of sepsis is muscle lactate accumulation. This study examined any putative (causative) association… Expand
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2007
2007
The purpose of this study was to determine whether pyruvate dehydrogenase kinase (PDK)4 was expressed in adipocytes and whether… Expand
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Highly Cited
2005
Highly Cited
2005
Cardiac ischemia and reperfusion are associated with loss in the activity of the mitochondrial enzyme pyruvate dehydrogenase (PDH… Expand
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