pyruvate dehydrogenase (acetyl-transferring) kinase

Known as: (pyruvate dehydrogenase (lipoamide))kinase, PDH kinase, pyruvate dehydrogenase kinase 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1998-2017
05101519982017

Papers overview

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Highly Cited
2013
Highly Cited
2013
Current drug development in oncology is non-selective as it typically focuses on pathways essential for the survival of all… (More)
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Highly Cited
2013
Highly Cited
2013
Most solid tumors are characterized by a metabolic shift from glucose oxidation to glycolysis, in part due to actively suppressed… (More)
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2013
2013
Pulmonary arterial hypertension (PAH) is a syndrome in which pulmonary vascular cross sectional area and compliance are reduced… (More)
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Highly Cited
2007
Highly Cited
2007
As a result of a spectrum of mitochondrial defects, tumor cells often preferentially use glycolysis to generate adenosine… (More)
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2005
2005
Cardiac ischemia and reperfusion are associated with loss in the activity of the mitochondrial enzyme pyruvate dehydrogenase (PDH… (More)
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2004
2004
Fasting forces adaptive changes in whole body and skeletal muscle metabolism that increase fat oxidation and decrease the… (More)
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2002
2002
Protein-protein interactions play an important role in the regulation of enzymic activity of pyruvate dehydrogenase kinase (PDK… (More)
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2001
2001
Fiber type specificity for expression of all three rat skeletal muscle pyruvate dehydrogenase kinase (PDK) isoforms (PDK1, 2, and… (More)
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Highly Cited
1998
Highly Cited
1998
This study investigated whether conditions known to alter the activity and phosphorylation state of the pyruvate dehydrogenase… (More)
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1998
1998
The dihydrolipoyl acetyltransferase (E2 component) is a 60-mer assembled via its COOH-terminal domain with exterior E1-binding… (More)
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