pyrimidine ribonucleoside triphosphate biosynthetic process

Known as: pyrimidine ribonucleoside triphosphate anabolism, pyrimidine ribonucleoside triphosphate synthesis, pyrimidine ribonucleoside triphosphate formation 
The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base… (More)
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
RNase H and Postreplication Repair Protect Cells from Ribonucleotides Incorporated in DNA
The chemical identity and integrity of the genome is challenged by the incorporation of ribonucleoside triphosphates (rNTPs) in… (More)
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2004
2004
General enzymatic screens identify three new nucleotidases in Escherichia coli. Biochemical characterization of SurE, YfbR, and YjjG.
To find proteins with nucleotidase activity in Escherichia coli, purified unknown proteins were screened for the presence of… (More)
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2002
2002
Directed evolution of novel polymerase activities: mutation of a DNA polymerase into an efficient RNA polymerase.
The creation of novel enzymatic function is of great interest, but remains a challenge because of the large sequence space of… (More)
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Highly Cited
1998
Highly Cited
1998
Unblocking of chain-terminated primer by HIV-1 reverse transcriptase through a nucleotide-dependent mechanism.
HIV-1 replication is inhibited by the incorporation of chain-terminating nucleotides at the 3' end of the growing DNA chain. Here… (More)
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Highly Cited
1998
Highly Cited
1998
Biochemical and kinetic analyses of NS5B RNA-dependent RNA polymerase of the hepatitis C virus.
The biochemical properties of the RNA-dependent RNA polymerase (RdRp) of the hepatitis C virus were analyzed. A hexahistidine… (More)
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1998
1998
Recombinant dengue virus type 1 NS3 protein exhibits specific viral RNA binding and NTPase activity regulated by the NS5 protein.
The full-length dengue virus NS3 protein has been successfully expressed as a 94-kDa GST fusion protein in Escherichia coli… (More)
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Highly Cited
1994
Highly Cited
1994
ATPase and GTPase activities associated with Semliki Forest virus nonstructural protein nsP2.
The replication of Semliki Forest virus requires four nonstructural proteins (nsP1 to nsP4), all derived from the same… (More)
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1992
1992
Preparation of isotopically labeled ribonucleotides for multidimensional NMR spectroscopy of RNA.
A general method for large scale preparation of uniformly isotopically labeled ribonucleotides and RNAs is described. Bacteria… (More)
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1992
1992
Coordinated leading- and lagging-strand synthesis at the Escherichia coli DNA replication fork. I. Multiple effectors act to modulate Okazaki fragment size.
The coordinated action of many enzymatic activities is required at the DNA replication fork to ensure the error-free, efficient… (More)
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1962
1962
The role of deoxyribonucleic acid in ribonucleic acid synthesis. III. The inhibition of the enzymatic synthesis of ribonucleic acid and deoxyribonucleic acid by actinomycin D and proflavin.
It has become evident that several enzymatic reactions exist which lead to the incorporation of the mononucleotide moiety of the… (More)
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