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pyrazolopyridine

 
National Institutes of Health

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2017
2017
Diarrhoeal disease is responsible for 8.6% of global child mortality. Recent epidemiological studies found the protozoan parasite… Expand
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2017
2017
A series of pyrazolo(dihydro)pyridines was synthesized and evaluated for antileishmanial efficacy against experimental visceral… Expand
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2012
2012
Cell potent inhibitors of B-Raf(V600E) that bind to the kinase in the DFG-out conformation are reported. These compounds utilize… Expand
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2011
2011
The V600E mutation of B-Raf kinase results in constitutive activation of the MAPK signaling pathway and is present in… Expand
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2008
2008
Potent and selective inhibitors of tumor necrosis factor-alpha converting enzyme (TACE) were discovered with several new… Expand
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2004
2004
The bifunctional pyrazolopyridine (2) and pyrano-pyrazole (3) derivatives were prepared by the reaction of 2-(2,4-dinitrophenyl… Expand
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Highly Cited
2002
Highly Cited
2002
Sphingosine 1-phosphate (Sph-1-P), a bioactive lysophospholipid capable of inducing a wide spectrum of biological responses, acts… Expand
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Highly Cited
2001
Highly Cited
2001
Nitric oxide (NO) is a widespread, potent, biological mediator that has many physiological and pathophysiological roles. Research… Expand
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1997
1997
1. The pharmacological profile of adenosine A1 receptors in human, guinea-pig, rat and mouse brain membranes was characterized in… Expand
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1983
1983
The binding of the novel ligand [3H]Ro 5-4864 to membrane preparations of rat kidney and brain was studied. [3H]Ro 5-4864 binds… Expand
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