purmorphamine

 
National Institutes of Health

Papers overview

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2014
2014
Neural stem cells (NSCs) provide promising therapeutic potential for cell replacement therapy in spinal cord injury (SCI… (More)
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2012
2012
Several biological events are controlled by Hedgehog (Hh) signaling, including osteoblast phenotype development. This study aimed… (More)
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2011
2011
Transplantation of neural stem cells (NSCs) is a promising therapeutic approach for Huntington's disease (HD). HD is… (More)
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Review
2010
Review
2010
Sonic hedgehog (Shh) is the most widely characterized of the three vertebrate Hedgehog homologs, and is essential for proper… (More)
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Highly Cited
2009
Highly Cited
2009
We have devised a reproducible protocol by which human embryonic stem cells (hESCs) or inducible pluripotent stem cells (iPSCs… (More)
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Highly Cited
2008
Highly Cited
2008
Specification of distinct cell types from human embryonic stem cells (hESCs) is key to the potential application of these naïve… (More)
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Highly Cited
2006
Highly Cited
2006
Hedgehog (Hh) signaling is an important regulator of embryonic patterning, tissue regeneration, stem cell renewal and cancer… (More)
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2005
2005
Purmorphamine is a novel small molecule with osteogenesis-inducing activity in multipotent mesenchymal progenitor cells, but… (More)
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Highly Cited
2004
Highly Cited
2004
Previously, a small molecule, purmorphamine, was identified that selectively induces osteogenesis in multipotent mesenchymal… (More)
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2002
2002
Purmorphamine, which is a 2,6,9-trisubstituted purine compound, was discovered through cell-based high-throughput screening from… (More)
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