purinoceptor P2Z

Known as: Purinoceptors, P2X7, P2Z Receptor, P2X7 Purinoceptor 
A purinergic P2X neurotransmitter receptor that plays a role in pain sensation signaling and regulation of inflammatory processes.
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Interleukin-1β (IL-1β) plays a central role in stimulation of innate immune system and inflammation and in several chronic… (More)
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Highly Cited
2012
Highly Cited
2012
The P2X7 receptor is an ATP-gated ion channel known for its cytotoxic activity. However, recent evidence suggests a role for P2X7… (More)
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Highly Cited
2007
Highly Cited
2007
Interleukin-1beta (IL-1beta) is a pro-inflammatory cytokine that plays an important role in host defense and inflammatory… (More)
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Highly Cited
2005
Highly Cited
2005
The P2X(7) purinoceptor is a ligand-gated cation channel, expressed predominantly by cells of immune origin, with a unique… (More)
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Highly Cited
2004
Highly Cited
2004
After a brain insult, ATP is released from injured cells and activates microglia. The microglia that are activated in this way… (More)
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Highly Cited
2004
Highly Cited
2004
P2X receptors are cationic-selective ion channels gated by extracellular ATP. There are seven subunits (P2X1-7), the first six of… (More)
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Highly Cited
1997
Highly Cited
1997
Mouse and human macrophages express a plasma membrane receptor for extracellular ATP named P2Z/P2X7. This molecule, recently… (More)
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Highly Cited
1997
Highly Cited
1997
Cells of the macrophage lineage express a peculiar surface receptor for extracellular ATP, designated P2Z/P2X7 purinergic… (More)
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Highly Cited
1996
Highly Cited
1996
The P2Z receptor is responsible for adenosine triphosphate (ATP)-dependent lysis of macrophages through the formation of membrane… (More)
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Highly Cited
1995
Highly Cited
1995
We have investigated responses of human monocyte/macrophage cells to extracellular ATP (ATPe). Freshly isolated peripheral blood… (More)
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