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purinergic receptor activity

Known as: purinoceptor, purinoreceptor 
Combining with a purine or purine derivative (purine nucleoside or purine nucleotide) and transmitting the signal from one side of the membrane to… Expand
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

Purinoceptorpurinergic receptor signaling pathway
extracellular ATP-gated cation channel activity

Narrower (1)

purinergic nucleotide receptor activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
An introduction to the roles of purinergic signalling in neurodegeneration, neuroprotection and neuroregeneration
Purinergic signalling appears to play important roles in neurodegeneration, neuroprotection and neuroregeneration. Initially… Expand
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Highly Cited
2012
Highly Cited
2012
Extracellular ATP mediates mast cell-dependent intestinal inflammation through P2X7 purinoceptors
Mast cells are known effector cells in allergic and inflammatory diseases, but their precise roles in intestinal inflammation… Expand
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Highly Cited
2007
Highly Cited
2007
Single domain antibodies from llama effectively and specifically block T cell ecto‐ADP‐ribosyltransferase ART2.2 in vivo
The purpose of our study was to develop a tool for blocking the function of a specific leukocyte ecto‐enzyme in vivo. ART2.2 is a… Expand
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Highly Cited
2003
Highly Cited
2003
NAD-induced T cell death: ADP-ribosylation of cell surface proteins by ART2 activates the cytolytic P2X7 purinoceptor.
T cells express a toxin-related ADP-ribosylating ectoenzyme, ART2. Exposure of mature T cells to NAD, the substrate for ADP… Expand
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Highly Cited
2002
Highly Cited
2002
Mutational Analysis of the Conserved Cysteines of the Rat P2X2 Purinoceptor
P2X receptors are ATP-gated cation channels that are widely expressed in the brain. The extracellular domains of all seven P2X… Expand
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Highly Cited
1997
Highly Cited
1997
Molecular characterization and pharmacological properties of the human P2X3 purinoceptor.
Using PCR and library screening techniques, a cDNA encoding an ATP ligand-gated channel has been isolated from human heart. The… Expand
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Highly Cited
1997
Highly Cited
1997
Interleukin-1 Enhances the ATP-Evoked Release of Arachidonic Acid from Mouse Astrocytes
During neuropathological states associated with inflammation, the levels of cytokines such as interleukin-1β (IL-1β) are… Expand
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Review
1996
Review
1996
Purinergic receptors: their role in nociception and primary afferent neurotransmission
The recent discovery of a P2X purinoceptor (a ligand-gated ion channel triggered by ATP) that is selectively expressed by small… Expand
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Highly Cited
1996
Highly Cited
1996
Pressure-mediated vasoconstriction of juxtamedullary afferent arterioles involves P2-purinoceptor activation.
This study was conducted to examine the hypothesis that P2 purinoceptors contribute to pressure-induced autoregulatory… Expand
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Highly Cited
1992
Highly Cited
1992
PPADS, a novel functionally selective antagonist of P2 purinoceptor-mediated responses.
We have characterized PPADS (pyridoxalphosphate-6-azophenyl-2',4'-disulfonic acid) as a novel antagonist which selectively blocks… Expand
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