purinergic receptor activity

Known as: purinoceptor, purinoreceptor 
Combining with a purine or purine derivative (purine nucleoside or purine nucleotide) and transmitting the signal from one side of the membrane to… (More)
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

Purinoceptorpurinergic receptor signaling pathway
extracellular ATP-gated cation channel activity

Narrower (1)

purinergic nucleotide receptor activity

Papers overview

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Review
2016
Review
2016
An introduction to the roles of purinergic signalling in neurodegeneration, neuroprotection and neuroregeneration
Purinergic signalling appears to play important roles in neurodegeneration, neuroprotection and neuroregeneration. Initially… (More)
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2007
2007
Single domain antibodies from llama effectively and specifically block T cell ecto-ADP-ribosyltransferase ART2.2 in vivo.
The purpose of our study was to develop a tool for blocking the function of a specific leukocyte ecto-enzyme in vivo. ART2.2 is a… (More)
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Highly Cited
2004
Highly Cited
2004
P2X7 receptor modulation of β-amyloid- and LPS-induced cytokine secretion from human macrophages and microglia
To test whether extracellular ATP can play a role in the neuroimmunopathology of Alzheimer's disease (AD), we evaluated the… (More)
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Highly Cited
2003
Highly Cited
2003
NAD-induced T cell death: ADP-ribosylation of cell surface proteins by ART2 activates the cytolytic P2X7 purinoceptor.
T cells express a toxin-related ADP-ribosylating ectoenzyme, ART2. Exposure of mature T cells to NAD, the substrate for ADP… (More)
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2000
2000
Cellular localization of P2Y(2) purinoceptor in rat renal inner medulla and lung.
Physiological and pharmacological studies have demonstrated that extracellular ATP, acting through P2Y(2) purinoceptor, modulates… (More)
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Highly Cited
1998
Highly Cited
1998
Molecular and Biological Characterization of the Murine Leukotriene B4 Receptor Expressed on Eosinophils
The movement of leukocytes into tissues is regulated by the local production of chemical mediators collectively referred to as… (More)
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1997
1997
Interleukin-1 enhances the ATP-evoked release of arachidonic acid from mouse astrocytes.
During neuropathological states associated with inflammation, the levels of cytokines such as interleukin-1beta (IL-1beta) are… (More)
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1997
1997
Overexpression of P2Y2 purinoceptor in intimal lesions of the rat aorta.
Extracellular nucleotides, particularly ATP, are involved in the modulation of arterial vasomotricity via P2 purinoceptors… (More)
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1995
1995
Extracellular ATP stimulates adenylyl cyclase and phospholipase C through distinct purinoceptors in NG108-15 cells.
In neuroblastoma x glioma hybrid NG108-15 cells, ATP induced a concentration-dependent increase in the intracellular Ca2… (More)
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Highly Cited
1990
Highly Cited
1990
Suramin antagonizes responses to P2-purinoceptor agonists and purinergic nerve stimulation in the guinea-pig urinary bladder and taenia coli.
1. Suramin, an inhibitor of several types of ATPase, was investigated for its ability to antagonize responses mediated via P2X… (More)
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