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protolichesterinic acid

National Institutes of Health

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2 relations

Broader (1)

4-Butyrolactone
analogs & derivatives

Papers overview

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Highly Cited
2014
Highly Cited
2014
Butyrolactone synthesis via polar radical crossover cycloaddition reactions: diastereoselective syntheses of methylenolactocin and protolichesterinic acid.
A direct catalytic synthesis of γ-butyrolactones from simple alkene and unsaturated acid starting materials is reported. The… 
2014
2014
Effects of anti-proliferative lichen metabolite, protolichesterinic acid on fatty acid synthase, cell signalling and drug response in breast cancer cells.
BACKGROUND The lichen compound (+)-protolichesterinic acid (+)-PA, isolated from Iceland moss, has anti-proliferative effects on… 
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Highly Cited
2013
Highly Cited
2013
Cytotoxic Activity and Antioxidant Capacity of Purified Lichen Metabolites: An In Vitro Study
The purpose of this study was to investigate the effects of six lichen metabolites (diffractaic acid, lobaric acid, usnic acid… 
Highly Cited
2012
Highly Cited
2012
Effect of vicanicin and protolichesterinic acid on human prostate cancer cells: role of Hsp70 protein.
With the aim of identifying novel agents with antigrowth and pro-apoptotic activity on prostate cancer cells, in the present… 
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Highly Cited
2003
Highly Cited
2003
The Antimicrobial Activity of Extracts of the Lichen Cetraria aculeata and Its Protolichesterinic Acid Constituent
Abstract In this study, the antimicrobial activity of the acetone, diethyl ether and ethanol extracts of the lichen Cetraria… 
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Review
1998
Review
1998
Plant-derived leading compounds for chemotherapy of human immunodeficiency virus (HIV) infection.
Many compounds of plant origin have been identified that inhibit different stages in the replication cycle of human… 
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Highly Cited
1998
Highly Cited
1998
Antimycobacterial activity of lichen metabolites in vitro.
Several compounds, whose structures represent the most common chemical classes of lichen metabolites, were screened for in vitro… 
Highly Cited
1998
Highly Cited
1998
Natural Products: Anti‐proliferative Effects of Lichen‐derived Inhibitors of 5‐Lipoxygenase on Malignant Cell‐lines and Mitogen‐stimulated Lymphocytes
Several lichen species have been used traditionally as medicinal plants. It has previously been shown that two low‐molecular… 
Highly Cited
1997
Highly Cited
1997
In vitro susceptibility of Helicobacter pylori to protolichesterinic acid from the lichen Cetraria islandica
With reference to the traditional use of Cetraria islandica (Iceland moss) for relief of gastric and duodenal ulcer, plant… 
1994
1994
In vitro inhibition of 5-lipoxygenase by protolichesterinic acid from Cetraria islandica.
The aliphatic α-methylene-γ-lactone (+)-protolichesterinic acid (1), isolated from Cetraria islandica, has been shown to exhibit… 
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