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proto-oncogene protein Spi-1

Known as: 31 kDa-Transforming Protein, SPI1, SPI1 Protein 
Transcription factor PU.1 (270 aa, ~31 kDa) is encoded by the human SPI1 gene. This protein plays a role in transcriptional regulation in… Expand
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
Developmental pathways that orchestrate the fleeting transition of endothelial cells into haematopoietic stem cells remain… Expand
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Review
2012
Review
2012
Host-adapted strains of Salmonella enterica cause systemic infections and have the ability to persist systemically for long… Expand
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Highly Cited
2011
Highly Cited
2011
BackgroundMyelodysplastic syndrome with isolated chromosome 5q deletion (5q- syndrome) is a clonal stem cell disorder… Expand
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Highly Cited
2010
Highly Cited
2010
The Spi1/Pu.1 transcription factor plays a crucial role in myeloid cell development in vertebrates. Despite extensive studies of… Expand
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Highly Cited
2008
Highly Cited
2008
The biogenesis of the Salmonella-containing vacuole within mammalian cells has been intensively studied over recent years… Expand
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Highly Cited
2008
Highly Cited
2008
BackgroundSalmonella enterica serovar Typhimurium (Typhimurium) is an important pathogen that infects a broad range of hosts. In… Expand
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2007
2007
Transcription factors play a crucial role during hematopoiesis by orchestrating lineage commitment and determining cellular fate… Expand
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Highly Cited
2002
Highly Cited
2002
The mammalian transcription factor SPI-1 (synonyms: SPI1, PU.1, or Sfpi1) plays a critical role in myeloid development. To… Expand
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Highly Cited
1999
Highly Cited
1999
Salmonellae encode two virulence-associated type III secretion systems (TTSS) within Salmonella pathogenicity islands 1 and 2… Expand
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Highly Cited
1998
Highly Cited
1998
The Salmonella typhimurium genome contains two pathogenicity islands (SPI) with genes encoding type III secretion systems for… Expand
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