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proteoglycan catabolic process

Known as: proteoglycan breakdown, proteoglycan catabolism, proteoglycan degradation 
The chemical reactions and pathways resulting in the breakdown of proteoglycans, any glycoprotein in which the carbohydrate units are… 
National Institutes of Health

Papers overview

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2005
2005
Differential Effects of Fibronectin Fragment on Proteoglycan Metabolism by Intervertebral Disc Cells: A Comparison With Articular Chondrocytes
Study Design. This in vitro study used the alginate bead culture system to probe for differences in the effects of fibronectin… 
2004
2004
Antioxidant and antiinflammatory activities of ventol, a phlorotannin-rich natural agent derived from Ecklonia cava, and its effect on proteoglycan degradation in cartilage explant culture.
Osteoarthritis is thought to be induced by the aging-related loss of homeostatic balance between degeneration and repair… 
1998
1998
Partial purification of heparanase activities in Chinese hamster ovary cells: evidence for multiple intracellular heparanases.
Heparanases are mammalian endoglycosidases that cleave heparan sulphate glycosaminoglycans from proteoglycan core proteins and… 
1995
1995
Interleukin-1 receptor antagonist inhibits proteoglycan breakdown in antigen induced but not polycation induced arthritis in the rabbit.
OBJECTIVE To compare the alterations in proteoglycan metabolism in antigen induced arthritis and polycation induced arthritis and… 
1992
1992
Characterization of proteoglycan degradation by calpain.
Degradation of cartilage proteoglycans was investigated under neutral conditions (pH 7.5) by using pig kidney calpain II (EC 3.4… 
1991
1991
Modulation of interleukin-1-induced alterations in cartilage proteoglycan metabolism by activation of protein kinase C.
Interleukin-1 (IL-1) stimulates proteoglycan degradation and prostaglandin E2 (PGE2) release and inhibits proteoglycan synthesis… 
1982
1982
Defective basal lamina formation by transformed mammary epithelial cells: A reduced effect of collagen on basal lamina (heparan sulfate‐rich) proteoglycan degradation
Invasive, spontaneously transformed mammary epithelial cells derived from the normal NMuMG cell line have lost the ability of… 
1982
1982
Enhanced breakdown of bovine articular cartilage proteoglycans by conditioned synovial medium. The effect of serum and dextran sulphate.
Medium from cultured bovine synovial membrane when applied to articular cartilage from the same animal enhanced proteoglycan… 
1977
1977
Phytomitogen-induced, lymphokine-mediated cartilage proteoglycan degradation.
The significance of T-cell activation in the immunopathogenesis of articular disease has been studied in an in vitro model to… 
1975
1975
The secretion of enzymes into the pericellular environment.
Connective tissue cells are capable of both synthesizing and degrading the macromolecular components of the extracellular matrix… 
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