Skip to search formSkip to main contentSkip to account menu
You are currently offline. Some features of the site may not work correctly.

proteoglycan catabolic process

Known as: proteoglycan breakdown, proteoglycan catabolism, proteoglycan degradation 
The chemical reactions and pathways resulting in the breakdown of proteoglycans, any glycoprotein in which the carbohydrate units are… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
OBJECTIVE Traumatic joint injury can damage cartilage and release inflammatory cytokines from adjacent joint tissue. The present… 
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Highly Cited
2008
Highly Cited
2008
OBJECTIVE Overproduction of nitric oxide (NO) and prostaglandin E(2) (PGE(2)) plays an important role in the pathogenesis of… 
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Highly Cited
2006
Highly Cited
2006
Intervertebral disc degeneration occurs commonly and is linked to persistent back pain and the development of disc herniation… 
Highly Cited
2002
Highly Cited
2002
OBJECTIVE To examine cyclooxygenase-2 (COX-2) enzyme expression, its regulation by interleukin-1 beta (IL-1 beta), and the role… 
Review
2000
Review
2000
The increased catabolism of the cartilage proteoglycan aggrecan is a principal pathological process which leads to the… 
Highly Cited
1998
Highly Cited
1998
OBJECTIVE To evaluate the relationship between specific cleavage of aggrecan at the Glu373-Ala374 'aggrecanase' site and… 
Highly Cited
1995
Highly Cited
1995
Monoclonal antibodies have been prepared that react specifically with the neoepitopes present on proteoglycan degradation… 
Highly Cited
1993
Highly Cited
1993
OBJECTIVE To investigate mechanisms of cartilage matrix destruction by a study of the effects of a specific inactivator of… 
Highly Cited
1993
Highly Cited
1993
The modulation of interleukin 1 (IL-1) effects on proteoglycan metabolism in intact murine patellar cartilage by transforming… 
Highly Cited
1984
Highly Cited
1984
Homogeneous catabolin from pig leucocytes induced proteoglycan breakdown, but not collagen breakdown, in explants of articular…