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proteoglycan biosynthetic process
Known as:
proteoglycan synthesis
, proteoglycan formation
, proteoglycan anabolism
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The chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are…
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National Institutes of Health
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Related topics
Related topics
2 relations
negative regulation of proteoglycan biosynthetic process
positive regulation of proteoglycan biosynthetic process
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1999
Highly Cited
1999
Notochordal cells interact with nucleus pulposus cells: regulation of proteoglycan synthesis.
D. Aguiar
,
S. L. Johnson
,
T. Oegema
Experimental cell research
1999
Corpus ID: 22758797
The disappearance of notochordal cells is correlated with early degenerative changes in the intervertebral disc. With increased…
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Highly Cited
1997
Highly Cited
1997
Evaluation of matrix scaffolds for tissue engineering of articular cartilage grafts.
D. Grande
,
C. Halberstadt
,
G. Naughton
,
R. Schwartz
,
R. Manji
Journal of biomedical materials research
1997
Corpus ID: 24624372
Injury to articular cartilage predisposes that joint to further degeneration and eventually osteoarthritis. Recent studies have…
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Highly Cited
1997
Highly Cited
1997
Effects of Hydrostatic Pressure on Matrix Synthesis and Matrix Metalloproteinase Production in the Human Lumbar Intervertebral Disc
Tadashi Handa
,
H. Ishihara
,
H. Ohshima
,
R. Osada
,
H. Tsuji
,
K. Obata
Spine
1997
Corpus ID: 46370217
Study Design. This study is a unique in vitro study on the effects of hydrostatic pressure on human intervertebral disc…
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Review
1995
Review
1995
Insulin-like growth factors and their binding proteins: biological actions.
J. I. Jones
,
D. Clemmons
Endocrine reviews
1995
Corpus ID: 10585320
I. Introduction THE insulin-like growth factors were discovered on the basis of their ability to stimulate cartilage sulfation…
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Highly Cited
1994
Highly Cited
1994
Nitric oxide mediates suppression of cartilage proteoglycan synthesis by interleukin-1.
D. Taşkıran
,
M. Stefanovic-Racic
,
H. Georgescu
,
C. Evans
Biochemical and biophysical research…
1994
Corpus ID: 22714709
Slices of rabbit articular cartilage synthesized large quantities of nitric oxide (NO) following exposure to human recombinant…
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Highly Cited
1994
Highly Cited
1994
Transforming growth factor-beta 1 stimulates articular chondrocyte proteoglycan synthesis and induces osteophyte formation in the murine knee joint.
H. V. van Beuningen
,
P. M. van der Kraan
,
O. Arntz
,
W. B. van den Berg
Laboratory investigation; a journal of technical…
1994
Corpus ID: 10900149
BACKGROUND High concentrations of active transforming growth factor-beta (TGF-beta) have been found in synovial fluids from…
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Highly Cited
1993
Highly Cited
1993
Direct transfer of transforming growth factor beta 1 gene into arteries stimulates fibrocellular hyperplasia.
E. Nabel
,
L. Shum
,
+7 authors
R. Derynck
Proceedings of the National Academy of Sciences…
1993
Corpus ID: 23107712
The arterial wall responds to thrombosis or mechanical injury through the induction of specific gene products that increase…
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Highly Cited
1990
Highly Cited
1990
Elevated expression of transforming growth factor-beta and proteoglycan production in experimental glomerulonephritis. Possible role in expansion of the mesangial extracellular matrix.
S. Okuda
,
L. Languino
,
E. Ruoslahti
,
W. Border
The Journal of clinical investigation
1990
Corpus ID: 28691345
Glomerular accumulation of extracellular matrix is a prominent feature of progressive glomerulonephritis. Previously, we have…
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Highly Cited
1986
Highly Cited
1986
Stimulation of proteoglycan biosynthesis by serum and insulin-like growth factor-I in cultured bovine articular cartilage.
D. McQuillan
,
C. Handley
,
M. Campbell
,
S. Bolis
,
V. E. Milway
,
A. Herington
The Biochemical journal
1986
Corpus ID: 450326
The addition of foetal calf serum to explant cultures of adult bovine articular cartilage is known to stimulate proteoglycan…
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Highly Cited
1982
Highly Cited
1982
Dedifferentiated chondrocytes reexpress the differentiated collagen phenotype when cultured in agarose gels
P. Benya
,
J. D. Shaffer
Cell
1982
Corpus ID: 26956828
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