protein tyrosine kinase PYK2

Known as: Cell Adhesion Kinase Beta, CADTK Protein, Proline Rich Tyrosine Kinase 2 
A non-receptor protein-tyrosine kinase that is expressed primarily in the BRAIN; OSTEOBLASTS; and LYMPHOID CELLS. In the CENTRAL NERVOUS SYSTEM focal… (More)
National Institutes of Health

Papers overview

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Review
2010
Review
2010
Focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (Pyk2) are related tyrosine kinases that have important cellular… (More)
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Highly Cited
2008
Highly Cited
2008
Focal adhesion kinase (FAK) plays a critical role during vascular development because knockout of FAK in endothelial cells (ECs… (More)
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Highly Cited
2004
Highly Cited
2004
The mechanisms involved in the mechanical loading-induced increase in bone formation remain unclear. In this study, we showed… (More)
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Highly Cited
2004
Highly Cited
2004
Many G protein-coupled receptors activate growth factor receptors, although the mechanisms controlling this transactivation are… (More)
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Highly Cited
2001
Highly Cited
2001
Stromal cell-derived factor-1 (SDF-1), the ligand for the CXCR4 receptor, is a highly efficacious chemoattractant for CD34… (More)
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Highly Cited
2000
Highly Cited
2000
The stromal cell-derived factor-1 (SDF-1) is an alpha chemokine that binds to the CXCR4 receptor. Knock-out studies in mice… (More)
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1998
1998
Several G protein-coupled receptors are known to direct the tyrosine phosphorylation, and in some cases the activation, of… (More)
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Highly Cited
1997
Highly Cited
1997
Many cells (e.g., epithelial cells) require attachment to the extracellular matrix (ECM) to survive, a phenomenon known as… (More)
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Highly Cited
1995
Highly Cited
1995
A second protein-tyrosine kinase (PTK) of the focal adhesion kinase (FAK) subfamily, cell adhesion kinase beta (CAK beta), was… (More)
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Highly Cited
1995
Highly Cited
1995
We have isolated a cDNA encoding a novel human intracytoplasmic tyrosine kinase, termed RAFTK (for a related adhesion focal… (More)
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