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protein serine/threonine kinase activity

Known as: protein serine-threonine kinase activity, serine(threonine) protein kinase activity, serine/threonine protein kinase activity 
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate… 
National Institutes of Health

Related topics

Related topics

4 relations
Cyclic AMP-Dependent Protein KinasesMAP Kinase GeneProtein Kinase C[acetyl-CoA carboxylase] kinase activity

Papers overview

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2019
2019
RIPK1 can mediate apoptosis in addition to necroptosis during embryonic development
RIPK1 has emerged as a key effector in programmed necrosis or necroptosis. This function of RIPK1 is mediated by its protein… 
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Review
2017
Review
2017
The mammalian ULK1 complex and autophagy initiation
Autophagy is a vital lysosomal degradation pathway that serves as a quality control mechanism. It rids the cell of damaged, toxic… 
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2014
2014
Identifying transcription factor complexes and their roles
Motivation: Eukaryotic gene expression is controlled through molecular logic circuits that combine regulatory signals of many… 
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Highly Cited
2013
Highly Cited
2013
Integrative Network Analysis Unveils Convergent Molecular Pathways in Parkinson's Disease and Diabetes
Background Shared dysregulated pathways may contribute to Parkinson's disease and type 2 diabetes, chronic diseases that afflict… 
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Highly Cited
2006
Highly Cited
2006
C-terminal truncation and Parkinson's disease-associated mutations down-regulate the protein serine/threonine kinase activity of PTEN-induced kinase-1.
The Parkinson's disease (PD) causative PINK1 gene encodes a mitochondrial protein kinase called PTEN-induced kinase 1 (PINK1… 
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Highly Cited
1997
Highly Cited
1997
A Casein Kinase I Activity Is Constitutively Associated with Nck*
Nck is a 47-kDa cytosolic protein devoid of intrinsic catalytic activity and consisting of Src homology 2 and 3 (SH2 and SH3… 
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Highly Cited
1996
Highly Cited
1996
Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse.
DNA-dependent protein kinase (DNA-PK) consists of a heterodimeric protein (Ku) and a large catalytic subunit (DNA-PKcs). The Ku… 
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Highly Cited
1994
Highly Cited
1994
Autophosphorylation of molluscan twitchin and interaction of its kinase domain with calcium/calmodulin.
An approximately 750-kDa member of the family of giant titin/twitchin-like myosin-associated proteins was highly purified from… 
Highly Cited
1993
Highly Cited
1993
The human cot proto-oncogene encodes two protein serine/threonine kinases with different transforming activities by alternative initiation of translation.
The cot gene is an oncogene encoding serine/threonine kinases isolated by DNA transfection assay. In this study, we isolated cDNA… 
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Highly Cited
1990
Highly Cited
1990
The hepatitis B virus-encoded transcriptional trans-activator hbx appears to be a novel protein serine/threonine kinase
To study the functional mechanism of the hepatitis B virus (HBV) X (hbx) gene product, we have expressed the hbx protein in E… 
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