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protein serine/threonine kinase activity
Known as:
protein serine-threonine kinase activity
, serine(threonine) protein kinase activity
, serine/threonine protein kinase activity
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate…
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National Institutes of Health
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Related topics
Related topics
4 relations
Cyclic AMP-Dependent Protein Kinases
MAP Kinase Gene
Protein Kinase C
[acetyl-CoA carboxylase] kinase activity
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2019
Highly Cited
2019
RIPK1 can mediate apoptosis in addition to necroptosis during embryonic development
Xuhua Zhang
,
J. Dowling
,
Jianke Zhang
Cell Death and Disease
2019
Corpus ID: 76660494
RIPK1 has emerged as a key effector in programmed necrosis or necroptosis. This function of RIPK1 is mediated by its protein…
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Review
2017
Review
2017
The mammalian ULK1 complex and autophagy initiation
Maria Zachari
,
I. Ganley
Essays in Biochemistry
2017
Corpus ID: 4579251
Autophagy is a vital lysosomal degradation pathway that serves as a quality control mechanism. It rids the cell of damaged, toxic…
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Highly Cited
2013
Highly Cited
2013
Integrative Network Analysis Unveils Convergent Molecular Pathways in Parkinson's Disease and Diabetes
Jose A. Santiago
,
J. Potashkin
PLoS ONE
2013
Corpus ID: 18174072
Background Shared dysregulated pathways may contribute to Parkinson's disease and type 2 diabetes, chronic diseases that afflict…
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Highly Cited
2006
Highly Cited
2006
C-terminal truncation and Parkinson's disease-associated mutations down-regulate the protein serine/threonine kinase activity of PTEN-induced kinase-1.
C. H. Sim
,
D. S. Lio
,
+4 authors
Heung-Chin Cheng
Human Molecular Genetics
2006
Corpus ID: 33044679
The Parkinson's disease (PD) causative PINK1 gene encodes a mitochondrial protein kinase called PTEN-induced kinase 1 (PINK1…
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Highly Cited
1997
Highly Cited
1997
A Casein Kinase I Activity Is Constitutively Associated with Nck*
Genevieve Lussier
,
L. Larose
Journal of Biological Chemistry
1997
Corpus ID: 43312987
Nck is a 47-kDa cytosolic protein devoid of intrinsic catalytic activity and consisting of Src homology 2 and 3 (SH2 and SH3…
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Highly Cited
1996
Highly Cited
1996
Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse.
T. Blunt
,
D. Gell
,
+4 authors
P. Jeggo
Proceedings of the National Academy of Sciences…
1996
Corpus ID: 7907137
DNA-dependent protein kinase (DNA-PK) consists of a heterodimeric protein (Ku) and a large catalytic subunit (DNA-PKcs). The Ku…
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Highly Cited
1994
Highly Cited
1994
Autophosphorylation of molluscan twitchin and interaction of its kinase domain with calcium/calmodulin.
J. Heierhorst
,
W. C. Probst
,
F. Vilim
,
A. Buku
,
K. R. Weiss
Journal of Biological Chemistry
1994
Corpus ID: 39022897
An approximately 750-kDa member of the family of giant titin/twitchin-like myosin-associated proteins was highly purified from…
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Highly Cited
1993
Highly Cited
1993
The human cot proto-oncogene encodes two protein serine/threonine kinases with different transforming activities by alternative initiation of translation.
M. Aoki
,
F. Hamada
,
T. Sugimoto
,
S. Sumida
,
T. Akiyama
,
K. Toyoshima
Journal of Biological Chemistry
1993
Corpus ID: 26691039
Highly Cited
1990
Highly Cited
1990
The hepatitis B virus-encoded transcriptional trans-activator hbx appears to be a novel protein serine/threonine kinase
Jane Y. Wu
,
Zhuo Zhou
,
A. Judd
,
C. Cartwright
,
W. Robinson
Cell
1990
Corpus ID: 10661603
1988
1988
The histidine-221 to tyrosine substitution in v-mos abolishes its biological function and its protein kinase activity.
B. Singh
,
C. Wittenberg
,
M. Hannink
,
S. Reed
,
D. Donoghue
,
R. Arlinghaus
Virology
1988
Corpus ID: 24345402
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