protein repair

The process of restoring a protein to its original state after damage by such things as oxidation or spontaneous decomposition of residues. [GOC:mlg]
National Institutes of Health

Papers overview

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Review
2014
Review
2014
Protein damage, repair and proteolysis.
Proteins are continuously affected by various intrinsic and extrinsic factors. Damaged proteins influence several intracellular… (More)
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Review
2011
Review
2011
Oxidative stress-mediated regulation of proteasome complexes.
Oxidative stress has been implicated in aging and many human diseases, notably neurodegenerative disorders and various cancers… (More)
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Review
2010
Review
2010
Oxidized mitochondrial protein degradation and repair in aging and oxidative stress.
Proteins are main targets for oxidative damage that occurs during aging and in oxidative stress situations. Since the… (More)
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Review
2005
Review
2005
Biological significance of isoaspartate and its repair system.
Isomerization of L-aspartate and deamidation of L-asparagine in proteins or peptides dominantly give rise to L-isoaspartate by a… (More)
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Highly Cited
2002
Highly Cited
2002
L23 protein functions as a chaperone docking site on the ribosome
During translation, the first encounter of nascent polypeptides is with the ribosome-associated chaperones that assist the… (More)
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Review
2001
Review
2001
Oxidative stress and protein aggregation during biological aging
Biological aging is a fundamental process that represents the major risk factor with respect to the development of cancer… (More)
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Highly Cited
2001
Highly Cited
2001
Extension of the Drosophila lifespan by overexpression of a protein repair methyltransferase.
Atypical protein isoaspartyl residues arise spontaneously during the aging process from the deamidation of protein asparaginyl… (More)
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Highly Cited
1998
Highly Cited
1998
Levels of DnaK and DnaJ provide tight control of heat shock gene expression and protein repair in Escherichia coli.
The expression of heat shock genes in Escherichia coli is regulated by the antagonistic action of the transcriptional activator… (More)
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1994
1994
Hormonal and environmental responsiveness of a developmentally regulated protein repair L-isoaspartyl methyltransferase in wheat.
The L-isoaspartyl protein methyltransferase (EC 2.1.1.77) has been proposed to be involved in the repair of spontaneously damaged… (More)
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1987
1987
Conversion of isoaspartyl peptides to normal peptides: implications for the cellular repair of damaged proteins.
The hypothesis that cellular protein carboxyl-methylation reactions recognize altered aspartyl residues as part of a protein… (More)
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