protein phosphatase activity

Known as: phosphoprotein phosphatase activity, phosphoprotein phosphohydrolase activity 
Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Phosphatase and tensin homologue deleted on chromosome 10 (PTEN) is mutated or lost in 60% to 70% of advanced gliomas and is… (More)
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Highly Cited
2004
Highly Cited
2004
Ionizing radiation induces autophosphorylation of the ataxia-telangiectasia mutated (ATM) protein kinase on serine 1981; however… (More)
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Highly Cited
2004
Highly Cited
2004
The tumor suppressor PTEN (phosphatase and tensin homolog deleted on chromosome 10) is a lipid and protein phosphatase. We report… (More)
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Highly Cited
2001
Highly Cited
2001
The tumour suppressor gene PTEN/MMAC1/TEP1 encodes a dual-specificity phosphatase that recognizes phosphatidylinositol-3,4,5… (More)
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Highly Cited
1998
Highly Cited
1998
Long-term potentiation (LTP) at the Schaffer collateral-CA1 synapse involves interacting signaling components, including calcium… (More)
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Highly Cited
1996
Highly Cited
1996
BACKGROUND Mitosis is regulated by MPF (maturation promoting factor), the active form of Cdc2/28-cyclin B complexes. Increasing… (More)
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Highly Cited
1992
Highly Cited
1992
Phosphorylation by protein kinases has been established as a key factor in the regulation of cytoskeletal structure. However… (More)
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Highly Cited
1991
Highly Cited
1991
A simple and sensitive colorimetric assay for protein phosphatase activity based on the determination of released Pi by an… (More)
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Highly Cited
1989
Highly Cited
1989
Calyculin A and okadaic acid induce contraction in smooth muscle fibers. Okadaic acid is an inhibitor of phosphatase activity and… (More)
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Highly Cited
1982