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protein phosphatase activity

Known as: phosphoprotein phosphatase activity, phosphoprotein phosphohydrolase activity 
Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of… Expand
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
PTEN is a tumour suppressor with phosphatase activity in vitro against both lipids and proteins and other potential non-enzymatic… Expand
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Highly Cited
2004
Highly Cited
2004
Ionizing radiation induces autophosphorylation of the ataxia‐telangiectasia mutated (ATM) protein kinase on serine 1981; however… Expand
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Highly Cited
2004
Highly Cited
2004
The tumor suppressor PTEN (phosphatase and tensin homolog deleted on chromosome 10) is a lipid and protein phosphatase. We report… Expand
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Highly Cited
2003
Highly Cited
2003
Germline intragenic mutations in PTEN are associated with 80% of patients with Cowden syndrome (CS) and 60% of patients with… Expand
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Highly Cited
1998
Highly Cited
1998
Long-term potentiation (LTP) at the Schaffer collateral-CA1 synapse involves interacting signaling components, including calcium… Expand
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Highly Cited
1996
Highly Cited
1996
BACKGROUND Mitosis is regulated by MPF (maturation promoting factor), the active form of Cdc2/28-cyclin B complexes. Increasing… Expand
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Highly Cited
1995
Highly Cited
1995
C2- and C6-ceramides (N-acetylsphingosine and N-hexanoylsphingosine, respectively) abolished the stimulation of DNA synthesis by… Expand
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Highly Cited
1992
Highly Cited
1992
Phosphorylation by protein kinases has been established as a key factor in the regulation of cytoskeletal structure. However… Expand
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Highly Cited
1991
Highly Cited
1991
A simple and sensitive colorimetric assay for protein phosphatase activity based on the determination of released Pi by an… Expand
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Highly Cited
1989
Highly Cited
1989
Calyculin A and okadaic acid induce contraction in smooth muscle fibers. Okadaic acid is an inhibitor of phosphatase activity and… Expand
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