proteasome regulatory particle (sensu Eukarya) location
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The proteasome is the major ATP-dependent protease in eukaryotic cells, but limited structural information restricts a… Expand The regulation of Ubiquitin (Ub) conjugates generated by the complex network of proteins that promote the mammalian DNA double… Expand Tumor necrosis factor receptor-associated protein-1 (TRAP1) is a mitochondrial (MITO) antiapoptotic heat-shock protein. The… Expand Background: Proteasome substrates are recognized by (poly)ubiquitin receptors or mediated by ubiquitin-like domain-containing… Expand The proteasome is a protease that controls diverse processes in eukaryotic cells. Its regulatory particle (RP) initiates the… Expand The 26S proteasome (26SP) is a multi-subunit, multi-catalytic protease that is responsible for most of the cytosolic and nuclear… Expand Over the past 10 years, much progress has been made to understand the roles of the similar, yet distinct yeast SAGA and SLIK… Expand Promoter recruitment of the Saccharomyces cerevisiae SAGA histone acetyltransferase complex is required for RNA polymerase II… Expand We have developed S. cerevisiae as a model system for mechanistic studies of the 26S proteasome. The subunits of the yeast 19S… Expand The 19S proteasome regulatory particle plays a critical role in cellular proteolysis. However, recent reports have demonstrated… Expand