Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

propylisopropylacetamide

Known as: 2-isopropylvaleramide 
 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Allylisopropylacetamide
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Evaluation of the enantioselective antiallodynic and pharmacokinetic profile of propylisopropylacetamide, a chiral isomer of valproic acid amide
Propylisopropylacetamide (PID) is a chiral CNS-active constitutional isomer of valpromide, the amide derivative of the major… Expand
2007
2007
Potent anticonvulsant urea derivatives of constitutional isomers of valproic acid.
Valproic acid (VPA) is a major antiepileptic drug (AED); however, its use is limited by two life-threatening side effects… Expand
2004
2004
Structure–Pharmacokinetic Relationships in a Series of Valpromide Derivatives with Antiepileptic Activity
The following valpromide (VPD) derivatives were synthesized and their structure–pharmacokinetic relationships explored… Expand
Highly Cited
1986
Highly Cited
1986
Uroporphyrin accumulation produced by halogenated biphenyls in chick-embryo hepatocytes. Reversal of the accumulation by piperonyl butoxide.
Cultures of chick-embryo hepatocytes were used to study the mechanism by which 3,4,3',4'-tetrachlorobiphenyl and 2,4,5,3',4… Expand
  • figure 1
  • figure 2
  • table 2
  • table 1
  • table 4
Highly Cited
1984
Highly Cited
1984
Inhibition of uroporphyrinogen decarboxylase by halogenated biphenyls in chick hepatocyte cultures. Essential role for induction of cytochrome P-448.
Uroporphyrinogen decarboxylase (EC 4.1.1.37) activity was assayed in cultures of chick-embryo hepatocytes by the changes in… Expand
1984
1984
Repair of chromate-induced DNA damage in chick embryo hepatocytes.
The repair of DNA damage caused by chromate was examined in chick embryo hepatocytes. Treatment of chick embryo hepatocytes with… Expand
1983
1983
The carcinogen chromate causes DNA damage and inhibits drug-mediated induction of porphyrin accumulation and glucuronidation in chick embryo hepatocytes.
DNA damage by chromate in chick embryo hepatocytes has been correlated with the effect of chromate on inducible cell functions… Expand
  • figure 1
  • figure 3
  • figure 2
  • table I
  • figure 4
1982
1982
Increases in cytochrome p-450 in cultured hepatocytes mediated by 3- and 4-carbon alcohols.
The amount of cytochrome P-450 was increased to different extents after treatment of cultured chick embryo hepatocytes with n… Expand
Highly Cited
1979
Highly Cited
1979
Hormonal requirements for the induction of cytochrome P-450 in hepatocytes cultured in a serum-free medium.
Abstract Drug mediated induction of cytochrome P450 was studied in cultures of hepatocytes that had never been cultured in the… Expand
1974
1974
Drug-induced porphyrin biosynthesis--XII. Levels of cytochrome P-450 in chick embryo liver following administration of allylisopropylacetamide and propylisopropylacetamide.
Allylisopropylacetamide caused a decrease in the level of chick embryo liver cytochrome P-450 1 h after administration, followed… Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE