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propargylamine

Known as: propinylamine 
 

Topic mentions per year

Topic mentions per year

1974-2017
0102019742017

Related topics

Related topics

2 relations

Broader (2)

PargylinePropylamines

Related mentions per year

Related mentions per year

1949-2018
19401960198020002020
propargylamine
Pargyline
Propylamines

Papers overview

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2016
2016
ASS234, As a New Multi-Target Directed Propargylamine for Alzheimer's Disease Therapy
HIGHLIGHTS ASS2324 is a hybrid compound resulting from the juxtaposition of donepezil and the propargylamine PF9601N ASS2324 is a… (More)
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2008
2008
TVP1022 and propargylamine protect neonatal rat ventricular myocytes against doxorubicin-induced and serum starvation-induced cardiotoxicity.
We recently reported that propargylamine derivatives such as rasagiline (Azilect) and its S-isomer TVP1022 are neuroprotective… (More)
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2005
2005
Regulation of Bcl-2 family proteins, neurotrophic factors, and APP processing in the neurorescue activity of propargylamine.
The anti-Parkinson drug, rasagiline (N-propargyl-(1R)-aminoindan) promotes neuronal survival, via neuroprotective activity… (More)
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2003
2003
Anti-apoptotic function of propargylamine inhibitors of type-B monoamine oxidase
In Parkinson's disease and other neurodegenerative diseases, (- )deprenyl, an inhibitor of type B monoamine oxidase (MAO-B), has… (More)
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2003
2003
The importance of propargylamine moiety in the anti-Parkinson drug rasagiline and its derivatives in MAPK-dependent amyloid precursor protein processing.
Rasagiline [N-propargyl-(1R)-aminoindan] a highly potent selective irreversible monoamine oxidase (MAO)-B inhibitor exerts… (More)
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Highly Cited
2002
Highly Cited
2002
Propargylamines induce antiapoptotic new protein synthesis in serum- and nerve growth factor (NGF)-withdrawn, NGF-differentiated PC-12 cells.
(-)-Deprenyl and structurally related propargylamines increase neuronal survival independently of monoamine oxidase B (MAO-B… (More)
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2000
2000
Mechanism underlying anti-apoptotic activity of a (-)deprenyl-related propargylamine, rasagiline.
A potent inhibitor of type B monoamine oxidase, (-)deprenyl, is known to protect or rescue dying neurons, independent of… (More)
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2000
2000
Systemic administration of the propargylamine CGP 3466B prevents behavioural and morphological deficits in rats with 6-hydroxydopamine-induced lesions in the substantia nigra.
The ability of CGP 3466B to attenuate the behavioural and morphological consequences of experimentally induced cell death was… (More)
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1994
1994
Neurochemical and neuroprotective effects of some aliphatic propargylamines: new selective nonamphetamine-like monoamine oxidase B inhibitors.
Aliphatic N-propargylamines have recently been discovered to be highly potent, selective, and irreversible monoamine oxidase B… (More)
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1992
1992
Aliphatic propargylamines: potent, selective, irreversible monoamine oxidase B inhibitors.
A series of aliphatic propargylamine derivatives has been synthesized. Some of them possess highly potent, irreversible… (More)
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