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propargylamine
Known as:
propinylamine
Â
Â
Topic mentions per year
Topic mentions per year
1974-2017
0
10
20
1974
2017
Related topics
Related topics
2 relations
Broader (2)
Pargyline
Propylamines
Related mentions per year
Related mentions per year
1949-2018
1940
1960
1980
2000
2020
propargylamine
Pargyline
Propylamines
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
ASS234, As a New Multi-Target Directed Propargylamine for Alzheimer's Disease Therapy
José Marco-Contelles
,
Mercedes Unzeta
,
+6 authors
Lhassane Ismaili
Front. Neurosci.
2016
HIGHLIGHTS ASS2324 is a hybrid compound resulting from the juxtaposition of donepezil and the propargylamine PF9601N ASS2324 is a…Â
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2008
2008
TVP1022 and propargylamine protect neonatal rat ventricular myocytes against doxorubicin-induced and serum starvation-induced cardiotoxicity.
Yana Kleiner
,
Orit Bar-Am
,
+6 authors
Ofer Binah
Journal of cardiovascular pharmacology
2008
We recently reported that propargylamine derivatives such as rasagiline (Azilect) and its S-isomer TVP1022 are neuroprotective…Â
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2005
2005
Regulation of Bcl-2 family proteins, neurotrophic factors, and APP processing in the neurorescue activity of propargylamine.
Orit Bar-Am
,
Orly Weinreb
,
Tamar Amit
,
Moussa B. H. Youdim
FASEB journal : official publication of the…
2005
The anti-Parkinson drug, rasagiline (N-propargyl-(1R)-aminoindan) promotes neuronal survival, via neuroprotective activity…Â
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2003
2003
Anti-apoptotic function of propargylamine inhibitors of type-B monoamine oxidase
Makito Naoi
,
Wakako Maruyama
,
Moussa B. H. Youdim
,
P. Yu
,
Amohia Boulton
InflammoPharmacology
2003
In Parkinson's disease and other neurodegenerative diseases, (- )deprenyl, an inhibitor of type B monoamine oxidase (MAO-B), has…Â
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2003
2003
The importance of propargylamine moiety in the anti-Parkinson drug rasagiline and its derivatives in MAPK-dependent amyloid precursor protein processing.
Merav Yogev-Falach
,
Tamar Amit
,
Orit Bar-Am
,
Moussa B. H. Youdim
FASEB journal : official publication of the…
2003
Rasagiline [N-propargyl-(1R)-aminoindan] a highly potent selective irreversible monoamine oxidase (MAO)-B inhibitor exerts…Â
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Highly Cited
2002
Highly Cited
2002
Propargylamines induce antiapoptotic new protein synthesis in serum- and nerve growth factor (NGF)-withdrawn, NGF-differentiated PC-12 cells.
William G. Tatton
,
R M E Chalmers-Redman
,
+4 authors
Nadine A. Tatton
The Journal of pharmacology and experimental…
2002
(-)-Deprenyl and structurally related propargylamines increase neuronal survival independently of monoamine oxidase B (MAO-B…Â
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2000
2000
Mechanism underlying anti-apoptotic activity of a (-)deprenyl-related propargylamine, rasagiline.
Wakako Maruyama
,
T Yamamoto
,
Kosuke Kitani
,
Melissa Carrillo
,
Moussa B. H. Youdim
,
Makito Naoi
Mechanisms of ageing and development
2000
A potent inhibitor of type B monoamine oxidase, (-)deprenyl, is known to protect or rescue dying neurons, independent of…Â
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2000
2000
Systemic administration of the propargylamine CGP 3466B prevents behavioural and morphological deficits in rats with 6-hydroxydopamine-induced lesions in the substantia nigra.
Gerda Andringa
,
René van Oosten
,
+4 authors
A. R. Cools
The European journal of neuroscience
2000
The ability of CGP 3466B to attenuate the behavioural and morphological consequences of experimentally induced cell death was…Â
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1994
1994
Neurochemical and neuroprotective effects of some aliphatic propargylamines: new selective nonamphetamine-like monoamine oxidase B inhibitors.
P. H.-F. Yu
,
B. A. Davis
,
+4 authors
Amohia Boulton
Journal of neurochemistry
1994
Aliphatic N-propargylamines have recently been discovered to be highly potent, selective, and irreversible monoamine oxidase B…Â
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1992
1992
Aliphatic propargylamines: potent, selective, irreversible monoamine oxidase B inhibitors.
P. H.-F. Yu
,
B. A. Davis
,
Amohia Boulton
Journal of medicinal chemistry
1992
A series of aliphatic propargylamine derivatives has been synthesized. Some of them possess highly potent, irreversible…Â
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