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proclavaminic acid

Known as: D-threo-Pentonic acid, 5-amino-2,4,5-trideoxy-2-(2-oxo-1-azetidinyl)- 
National Institutes of Health

Papers overview

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2009
2009
Arginase is a binuclear manganese metalloenzyme that serves as a therapeutic target for the treatment of asthma, erectile… Expand
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2006
2006
(3R,5R)-Clavulanic acid, a clinically used inhibitor of serine β-lactamases, is produced by fermentation of Streptomyces… Expand
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Review
2004
Review
2004
The biosynthesis of clavulanic acid and related clavam metabolites is only now being elucidated. Understanding of this pathway… Expand
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2002
2002
During biosynthesis of the clinically used beta-lactamase inhibitor clavulanic acid, one of the three steps catalysed by… Expand
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Highly Cited
2001
Highly Cited
2001
Using a single ferrous active site, clavaminate synthase 2 (CS2) activates O(2) and catalyzes the hydroxylation of… Expand
1995
1995
Clavaminate synthase (CS), a key enzyme in the clavulanic acid biosynthetic pathway, has been purified to electrophoretic… Expand
Highly Cited
1990
Highly Cited
1990
A pivotal step in the biosynthetic pathway to the beta-lactamase inhibitor clavulanic acid is the conversion of proclavaminic… Expand