procarbazine/thalidomide

Cyclin-dependent kinase 9 (CDK9), an important regulator of transcriptional elongation, is a promising target for cancer therapy… (More)

BACKGROUND Hydroxyurea is a cytotoxic and myelosuppressive drug that has been used during recent years in the treatment of… (More)

INTRODUCTION hemoglobinopathies constitute a major health problem worldwide. These disorders are characterized by a clinical and… (More)

This paper summarizes the results on the epidemiology and molecular basis of thalassemias and other hemoglobinopathies in the… (More)

The palliation of patients with megaesophagus secondary to achalasia of the cardia presents significant challenges to the surgeon… (More)

In a recent study, it was reported that thalidomide may suppress mucosal, cutaneous and articular manifestations in the major i… (More)

The purpose of this study was to ascertain whether thalassemia heterozygotes (α thal) who have sickle cell anemia (SCA) suffer… (More)

Lepromatous leprosy patients experiencing erythema nodosum lepro­ sum (ENL) have been reported to have an increase in the ratio… (More)

Thalidomide treatment of patients suffering from leprosy reaction (LR ) was introduced in 1964 (3). This thcrapy has a striking… (More)

(p = 0.001). Earlier it has been demons t ra ted t h a t the chromosome breaks produced by 5-ftnorodeoxyuridine can be… (More)