presynaptic density protein 95

Known as: Synapse-Associated Protein 90, Postsynaptic Density-95, SAP90 
Disks large homolog 4 (724 aa, ~80 kDa) is encoded by the human DLG4 gene. This protein is involved in synaptic signal transmission.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1982-2017
0204019822017

Papers overview

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Highly Cited
2008
Highly Cited
2008
Long-term potentiation (LTP) is accompanied by dendritic spine growth and changes in the composition of the postsynaptic density… (More)
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Highly Cited
2007
Highly Cited
2007
Fragile X syndrome, a common form of inherited mental retardation, is caused by the loss of fragile X mental retardation protein… (More)
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Highly Cited
2007
Highly Cited
2007
Accumulation of AMPA receptors at synapses is a fundamental feature of glutamatergic synaptic transmission. Stargazin, a member… (More)
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Highly Cited
2006
Highly Cited
2006
Mutations in the genes for amyloid precursor protein (APP) and presenilins (PS1, PS2) increase production of beta-amyloid 42… (More)
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Highly Cited
2004
Highly Cited
2004
The regulated delivery of AMPA-type glutamate receptors (AMPARs) to synapses is an important mechanism underlying synaptic… (More)
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Highly Cited
2003
Highly Cited
2003
Previous studies have shown that overexpression of the protein PSD-95 (postsynaptic density-95) selectively enhances AMPA… (More)
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Highly Cited
2002
Highly Cited
2002
Dynamic regulation of AMPA-type glutamate receptors represents a primary mechanism for controlling synaptic strength, though… (More)
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Highly Cited
1998
Highly Cited
1998
Specific patterns of neuronal firing induce changes in synaptic strength that may contribute to learning and memory. If the… (More)
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Highly Cited
1996
Highly Cited
1996
Neuronal nitric oxide synthase (nNOS) is concentrated at synaptic junctions in brain and motor endplates in skeletal muscle. Here… (More)
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Highly Cited
1996
Highly Cited
1996
PSD-95, a prominent protein component of the postsynaptic density (PSD) fraction from rat forebrain, has been localized by light… (More)
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