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pregnane X receptor

Known as: nuclear receptor subfamily 1, group I, member 2, steroid and xenobiotic receptor (SXR), steroid X receptor 
 
National Institutes of Health

Papers overview

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2016
2016
Bisphenol A, one of the industrial chemicals used in plastics and in the coating of dishes and medical equipment, behaves as an… Expand
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2015
2015
1Clinical Research Center for Hair and Skin Science, Department of Dermatology and Allergy, Charité-Universitaetsmedizin Berlin… Expand
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2010
2010
Monkeys have been proposed as an animal model to predict the magnitude of human clinical drug-drug interactions caused by CYP3A4… Expand
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Highly Cited
2008
Highly Cited
2008
Pregnane X receptor (PXR) is a major transcription factor regulating the inducible expression of a variety of transporters and… Expand
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Highly Cited
2006
Highly Cited
2006
The pregnane X receptor (PXR) is an essential component of the body's detoxification system. PXR is activated by a broad spectrum… Expand
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Highly Cited
2004
Highly Cited
2004
BACKGROUND & AIMS Phase 1, phase 2, and cellular efflux transporters are critical components in intestinal barrier function… Expand
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Highly Cited
2002
Highly Cited
2002
Induction of cytochrome P450 3A4 (CYP3A4) is determined typically by employing primary culture of human hepatocytes and measuring… Expand
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Review
2002
Review
2002
The pregnane X receptor (PXR) is a promiscuous nuclear receptor that has evolved to protect the body from toxic chemicals. PXR is… Expand
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Highly Cited
2000
Highly Cited
2000
St John's wort (SJW), an extract of the medicinal plant Hypericum perforatum, is widely used as a herbal antidepressant. Recently… Expand
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