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pradigastat

 
National Institutes of Health

Papers overview

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2017
2017
Abstract 1. Pradigastat is a potent and specific diacylglycerol acyltransferase-1 (DGAT1) inhibitor effective in lowering… Expand
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2016
2016
Pradigastat, a novel diacylglycerol acyltransferase-1 inhibitor, has activity in common metabolic diseases associated with… Expand
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2016
2016
The DGAT1 inhibitor, pradigastat, demonstrated a mild phototoxicity signal in preclinical studies. Therefore, this clinical trial… Expand
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2016
2016
Pradigastat, a novel diacylglycerol acyltransferase 1 inhibitor, has been studied in familial chylomicronemia syndrome. To… Expand
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Highly Cited
2015
Highly Cited
2015
BackgroundFamilial chylomicronemia syndrome (FCS) is a rare lipid disease caused by complete lipoprotein lipase (LPL) deficiency… Expand
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2015
2015
Pradigastat is a potent and selective inhibitor of diacylglycerol acyltransferase 1, an enzyme highly expressed in the small… Expand
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2015
2015
OBJECTIVE An in vitro drugdrug interaction (DDI) study was performed to assess the potential for pradigastat to inhibit breast… Expand
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2015
2015
Background and ObjectivePradigastat, a novel diacylglycerol acyltransferase 1 inhibitor, is under development to treat familial… Expand
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2014
2014
Pradigastat, a novel diacylglycerol acyltransferase-1 inhibitor, was evaluated for both pharmacokinetic (PK) and pharmacodynamic… Expand
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