positive regulation of transforming growth factor beta activation

The adaptive response of connective tissue to loading requires increased synthesis and turnover of matrix proteins, with special… Expand

Ultraviolet (UV) irradiation from the sun reduces production of type I procollagen (COLI), the major structural protein in human… Expand

Smad proteins transduce signals from transforming growth factor-beta (TGF-beta) superfamily ligands that regulate cell… Expand

Interleukin (IL)-4 and IL-13 are key proinflammatory cytokines in asthma. Studies in transgenic mice show that both cytokines… Expand

Smads regulate transcription of defined genes in response to TGF-beta receptor activation, although the mechanisms of Smad… Expand

The biological activity of transforming growth factor β1 (TGF‐β) is controlled by its secretion as a latent complex in which it… Expand

The transforming growth factor βs (TGF-βs) are a group of multifunctional growth factors that inhibit cell cycle progression in… Expand

The Wilms' tumor suppressor gene (WT1) encodes a zinc finger DNA binding protein which functions as a transcriptional repressor… Expand

Loss of growth regulation by transforming growth factor-beta (TGF-beta) may be an important step in carcinogenesis. We have used… Expand

Platelet-derived growth factor (PDGF) and transforming growth factor-beta 1 (TGF-beta 1) increase [35S]sulfate incorporation into… Expand