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positive regulation of hypoxia-inducible factor-1alpha signaling pathway

Known as: positive regulation of HIF1alpha pathway, up regulation of hypoxia-inducible factor-1alpha signalling pathway, up regulation of HIF1alpha pathway 
Any process that activates or increases the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway. [GOC:bf, GOC:TermGenie… Expand
National Institutes of Health

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Related topics

2 relations

Broader (1)

biological control
hypoxia-inducible factor-1alpha signaling pathway

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Differential Response to 1,25-dihydroxyvitamin D in Metastatic and Non-Metastatic Breast Cancer Cell Lines in Hypoxia (P05-006-19).
Objectives Prevention of metastasis is of utmost importance for increasing survival in breast cancer patients. Oxygen tension is… Expand
2018
2018
Evaluation of Erythrocyte Changes After Normoxic Return from Hypoxia.
Hypoxia increases erythropoiesis by hypoxia-inducible factors (HIF), principally by HIF-2, which upregulates erythropoietin… Expand
2014
2014
Hinokitiol increases the angiogenic potential of dental pulp cells through ERK and p38MAPK activation and hypoxia-inducible factor-1α (HIF-1α) upregulation.
Hinokitiol, a natural iron-chelating agent, is known to have diverse biological and pharmacological activities in various cell… Expand
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2013
2013
Identification of the angiogenic gene signature induced by EGF and hypoxia in colorectal cancer
BackgroundColorectal cancer (CRC) is characterised by hypoxia, which activates gene transcription through hypoxia-inducible… Expand
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2012
2012
MT1-MMP plays a critical role in hematopoiesis by regulating HIF-mediated chemokine/cytokine gene transcription within niche cells.
HSC fate decisions are regulated by cell-intrinsic and cell-extrinsic cues. The latter cues are derived from the BM niche… Expand
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Highly Cited
2011
Highly Cited
2011
Suppression of dual-specificity phosphatase-2 by hypoxia increases chemoresistance and malignancy in human cancer cells.
Hypoxia inducible factor-1 (HIF-1) is the master transcriptional regulator of the cellular response to altered oxygen levels. HIF… Expand
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Highly Cited
2010
Highly Cited
2010
NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment
Hyperthermia (HT) is a strong adjuvant treatment with radiotherapy and chemotherapy because it causes tumor reoxygenation… Expand
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2009
2009
Bone marrow derived stromal cells modified by adenovirus-mediated HIF-1alpha double mutant protect cardiac myocytes against CoCl2-induced apoptosis.
Bone marrow derived stromal cells (MSCs) can prevent the apoptosis of ischemic cardiomyocytes (CMCs). This anti-apoptosis… Expand
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2007
2007
Hypoxia-induced IL-18 Increases Hypoxia-inducible Factor-1α Expression through a Rac1-dependent NF-κB Pathway
Interleukin-18 (IL-18) plays pivotal roles in linking inflammatory immune responses and tumor progression and metastasis, yet the… Expand
2005
2005
Peripheral T Cells under Hypoxic Conditions in Human Synthesis via Rapamycin-Sensitive Pathway Protein α Hypoxia-Inducible Factor-1 TCR Engagement Increases
 
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