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positive regulation of hypoxia-inducible factor-1alpha signaling pathway

Known as: positive regulation of HIF1alpha pathway, up regulation of hypoxia-inducible factor-1alpha signalling pathway, up regulation of HIF1alpha pathway 
Any process that activates or increases the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway. [GOC:bf, GOC:TermGenie… Expand
National Institutes of Health

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Broader (1)

biological control
hypoxia-inducible factor-1alpha signaling pathway

Papers overview

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2019
2019
Differential Response to 1,25-dihydroxyvitamin D in Metastatic and Non-Metastatic Breast Cancer Cell Lines in Hypoxia (P05-006-19).
Objectives Prevention of metastasis is of utmost importance for increasing survival in breast cancer patients. Oxygen tension is… Expand
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2018
2018
Evaluation of Erythrocyte Changes After Normoxic Return from Hypoxia.
Hypoxia increases erythropoiesis by hypoxia-inducible factors (HIF), principally by HIF-2, which upregulates erythropoietin… Expand
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2014
2014
Hinokitiol increases the angiogenic potential of dental pulp cells through ERK and p38MAPK activation and hypoxia-inducible factor-1α (HIF-1α) upregulation.
Hinokitiol, a natural iron-chelating agent, is known to have diverse biological and pharmacological activities in various cell… Expand
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2013
2013
Identification of the angiogenic gene signature induced by EGF and hypoxia in colorectal cancer
BackgroundColorectal cancer (CRC) is characterised by hypoxia, which activates gene transcription through hypoxia-inducible… Expand
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2012
2012
MT1-MMP plays a critical role in hematopoiesis by regulating HIF-mediated chemokine/cytokine gene transcription within niche cells.
HSC fate decisions are regulated by cell-intrinsic and cell-extrinsic cues. The latter cues are derived from the BM niche… Expand
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2011
2011
Suppression of dual-specificity phosphatase-2 by hypoxia increases chemoresistance and malignancy in human cancer cells.
Hypoxia inducible factor-1 (HIF-1) is the master transcriptional regulator of the cellular response to altered oxygen levels. HIF… Expand
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Highly Cited
2010
Highly Cited
2010
NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment.
Hyperthermia (HT) is a strong adjuvant treatment with radiotherapy and chemotherapy because it causes tumor reoxygenation… Expand
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2009
2009
Bone marrow derived stromal cells modified by adenovirus-mediated HIF-1alpha double mutant protect cardiac myocytes against CoCl2-induced apoptosis.
Bone marrow derived stromal cells (MSCs) can prevent the apoptosis of ischemic cardiomyocytes (CMCs). This anti-apoptosis… Expand
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2007
2007
Hypoxia-induced IL-18 Increases Hypoxia-inducible Factor-1α Expression through a Rac1-dependent NF-κB Pathway
Interleukin-18 (IL-18) plays pivotal roles in linking inflammatory immune responses and tumor progression and metastasis, yet the… Expand
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2005
2005
Peripheral T Cells under Hypoxic Conditions in Human Synthesis via Rapamycin-Sensitive Pathway Protein α Hypoxia-Inducible Factor-1 TCR Engagement Increases
 
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