positive regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade

Known as: up regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade, activation by symbiont of host I-kappaB kinase/NF-kappaB cascade, up-regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade 
Any process that activates or increases the frequency, rate or extent of host NF-kappaB-mediated signal transduction pathways during the host defense… (More)
National Institutes of Health

Papers overview

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Review
2010
Review
2010
Posttranslational modifications of NF-kappaB: another layer of regulation for NF-kappaB signaling pathway.
The eukaryotic transcription factor NF-kappaB regulates a wide range of host genes that control the inflammatory and immune… (More)
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Highly Cited
2009
Highly Cited
2009
A Wolbachia Symbiont in Aedes aegypti Limits Infection with Dengue, Chikungunya, and Plasmodium
Wolbachia are maternally inherited intracellular bacterial symbionts that are estimated to infect more than 60% of all insect… (More)
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Highly Cited
2009
Highly Cited
2009
KEAP1 E3 ligase-mediated downregulation of NF-kappaB signaling by targeting IKKbeta.
IkappaB kinase beta (IKKbeta) is involved in tumor development and progression through activation of the nuclear factor (NF… (More)
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Review
2009
Review
2009
NF-kappaB in the immune response of Drosophila.
The nuclear factor kappaB (NF-kappaB) pathways play a major role in Drosophila host defense. Two recognition and signaling… (More)
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Highly Cited
2006
Highly Cited
2006
Functional genomic and metabolic studies of the adaptations of a prominent adult human gut symbiont, Bacteroides thetaiotaomicron, to the suckling period.
The adult human gut microbiota is dominated by two divisions of Bacteria, the Bacteroidetes and the Firmicutes. Assembly of this… (More)
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Highly Cited
2006
Highly Cited
2006
IκBɛ provides negative feedback to control NF-κB oscillations, signaling dynamics, and inflammatory gene expression
NF-kappaB signaling is known to be critically regulated by the NF-kappaB-inducible inhibitor protein IkappaBalpha. The resulting… (More)
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Highly Cited
2005
Highly Cited
2005
Control of antiviral defenses through hepatitis C virus disruption of retinoic acid-inducible gene-I signaling.
Hepatitis C virus (HCV) is a major human pathogen that infects 170 million people. A hallmark of HCV is its ability to establish… (More)
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Highly Cited
2001
Highly Cited
2001
Mutations in the Drosophila dTAK1 gene reveal a conserved function for MAPKKKs in the control of rel/NF-kappaB-dependent innate immune responses.
In mammals, TAK1, a MAPKKK kinase, is implicated in multiple signaling processes, including the regulation of NF-kappaB activity… (More)
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Highly Cited
2001
Highly Cited
2001
CARD11 and CARD14 are novel caspase recruitment domain (CARD)/membrane-associated guanylate kinase (MAGUK) family members that interact with BCL10 and activate NF-kappa B.
The caspase recruitment domain (CARD) is a protein-binding module that mediates the assembly of CARD-containing proteins into… (More)
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Highly Cited
1997
Highly Cited
1997
The 18-wheeler mutation reveals complex antibacterial gene regulation in Drosophila host defense.
Mammals and insects employ similar Rel/NF-kappaB signaling cascades in their humoral immune responses. The mammalian interleukin… (More)
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