polynucleotide 5'-hydroxyl-kinase activity

Known as: polynucleotide 5'-hydroxyl kinase (phosphorylating) activity, 5'-hydroxyl polynucleotide kinase activity, polynucleotide 5'-hydroxy-kinase activity 
Catalysis of the reaction: NTP + 5'-dephosphopolynucleotide = NDP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA. [EC:2.7.1.78]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1986-2018
024619862018

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2014
2014
The phosphorylation of nucleic acid catalyzed by polynucleotide kinase is an indispensible procedure involved in many vital… (More)
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2014
2014
A label-free, oligonucleotide-based, switch-on luminescence detection method for T4 polynucleotide kinase activity has been… (More)
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2011
2011
XRCC1 is a scaffold protein capable of interacting with several DNA repair proteins. Here we provide evidence for the presence of… (More)
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2010
2010
Human DNA glycosylase NEIL1 exhibits a superior ability to remove oxidized guanine lesions guanidinohydantoin (Gh) and… (More)
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2009
2009
The DNA-binding inorganic compound cisplatin is one of the most successful anticancer drugs. The detailed mechanism by which… (More)
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2009
2009
We describe a novel method for real-time monitoring of the activity and kinetics of T4 polynucleotide kinase (PNK) by use of a… (More)
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2006
2006
DNA glycosylases/AP lyases initiate repair of oxidized bases in the genomes of all organisms by excising these lesions and then… (More)
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2006
2006
The dual function mammalian DNA repair enzyme, polynucleotide kinase (PNK), facilitates strand break repair through catalysis of… (More)
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2005
2005
Phosphorylation of nucleic acids is an indispensable process to repair strand interruption of nucleic acids. We have studied the… (More)
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1986
1986
An RNA ligase that catalyzes the formation of a 2'-phosphomonoester-3',5'-phosphodiester bond in the presence of ATP and Mg2+ was… (More)
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