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polyethylene glycol-recombinant human megakaryocyte growth and development factor

Known as: PEG-rHuMGDF, Polyethylene Glycosylated Recombinant Human MGDF, PEG Recombinant Human Megakaryocyte Growth and Development Factor 
A pegylated formulation containing a recombinant growth factor with thrombopoietic activity. The recombinant human megakaryocyte growth and… Expand
National Institutes of Health

Papers overview

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Review
2007
Review
2007
Although development of first-generation thrombopoietic growth factors (recombinant human thrombopoietin [TPO] and pegylated… Expand
Review
2002
Review
2002
Thrombocytopenia is a common medical problem for which the main treatment is platelet transfusion. Given the increasing use of… Expand
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Highly Cited
2001
Highly Cited
2001
Thrombocytopenia developed in some individuals treated with a recombinant thrombopoietin (TPO), pegylated recombinant human… Expand
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Highly Cited
2001
Highly Cited
2001
Thrombopoietin and its receptor (Mpl) support survival and proliferation in megakaryocyte progenitors and in BaF3 cells… Expand
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Highly Cited
1996
Highly Cited
1996
BACKGROUND Pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) is a potent stimulator of… Expand
Highly Cited
1996
Highly Cited
1996
The primary physiologic regulator of platelet production, Mpl ligand, has recently been cloned and characterized. To define the… Expand
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Highly Cited
1996
Highly Cited
1996
This report describes the effect of pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) on… Expand
Highly Cited
1993
Highly Cited
1993
The effects of recombinant human interleukin-11 (rhIL-11) on in vivo mouse megakaryocytopoeisis were examined. Normal C57Bl/6… Expand
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Highly Cited
1989
Highly Cited
1989
The effects of recombinant hemopoietic factors on the clonal growth of human megakaryocyte progenitors were explored using serum… Expand
Highly Cited
1988
Highly Cited
1988
Human megakaryocyte colony formation was observed in serum-free agar cultures with a medium containing deionized bovine serum… Expand