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poly(maleic acid-styrene)neocarzinostatin
Known as:
SMANCS
, copoly(styrene-maleic acid)neocarzinostatin
, zinostatin stimalamer
National Institutes of Health
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Related topics
Related topics
6 relations
Broader (4)
Antineoplastic Agents
Maleic Anhydrides
Polystyrenes
Zinostatin
Narrower (1)
YM 881
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Pelioid‐type hepatocellular carcinoma with numerous eosinophilic infiltrations in a patient with primary biliary cirrhosis
Takuya Watanabe
,
K. Aikawa
,
+7 authors
M. Nomoto
Hepatology Research
2008
Corpus ID: 6092800
A 65‐year‐old woman with liver injury was referred to our hospital in 1992. She was diagnosed with primary biliary cirrhosis (PBC…
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1998
1998
A novel dosage approach for evaluation of SMANCS [poly-(styrene-co-maleyl-half-n-butylate) - neocarzinostatin] in the treatment of primary hepatocellular carcinoma.
L. Seymour
,
S. Olliff
,
+6 authors
D. Kerr
International Journal of Oncology
1998
Corpus ID: 20453742
We report a Phase I/II clinical trial of poly-(styrene-co-maleyl-half-n-butylate)-neocarzinostatin (SMANCS) for intra-arterial…
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1990
1990
Comparison of the cytotoxic effects of the high- and low-molecular-weight anticancer agents on multidrug-resistant Chinese hamster ovary cells in vitro.
Y. Miyamoto
,
T. Oda
,
H. Maeda
Cancer Research
1990
Corpus ID: 6639351
Neocarzinostatin (NCS), styrene-maleic acid copolymer-conjugated neocarzinostatin (SMANCS), and ricin exhibited cytotoxicity…
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1990
1990
Role of natural killer cells and macrophages in the nonspecific resistance to tumors in mice stimulated with SMANCS, a polymer-conjugated derivative of neocarzinostatin.
F. Suzuki
,
R. Pollard
,
S. Uchimura
,
T. Munakata
,
H. Maeda
Cancer Research
1990
Corpus ID: 33908841
Copoly(styrene-maleic acid)-conjugated neocarzinostatin (SMANCS), a lipophilic derivative of the proteinaceous antitumor…
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1988
1988
Interferon induction by SMANCS: a polymer-conjugated derivative of neocarzinostatin.
F. Suzuki
,
T. Munakata
,
H. Maeda
Anticancer Research
1988
Corpus ID: 21768539
Poly (styrene-co-maleic acid)-conjugated neocarzinostatin, SMANCS, induced antiviral activities in the circulation of mice. The…
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Highly Cited
1987
Highly Cited
1987
Binding to and internalization by cultured cells of neocarzinostatin and enhancement of its actions by conjugation with lipophilic styrene-maleic acid copolymer.
T. Oda
,
H. Maeda
Cancer Research
1987
Corpus ID: 12459543
The binding of a copoly(styrene-maleic acid)-conjugated neocarzinostatin (NCS) designated as smancs (Mr 16,000), and parental NCS…
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1987
1987
Facilitated internalization of neocarzinostatin and its lipophilic polymer conjugate, SMANCS, into cytosol in acidic pH.
T. Oda
,
F. Sato
,
H. Maeda
Journal of the National Cancer Institute
1987
Corpus ID: 26110312
The effects of environmental pH on the binding and cytotoxicity of the antitumor proteins neocarzinostatin (NCS) and SMANCS…
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1987
1987
Tumor-targeted chemotherapy with lipid contrast medium and macromolecular anticancer drug (SMANCS) for renal cell carcinoma.
M. Kobayashi
,
K. Imai
,
S. Sugihara
,
H. Maeda
,
T. Konno
,
H. Yamanaka
Urology
1987
Corpus ID: 9665980
1982
1982
In vitro mode of action, pharmacokinetics, and organ specificity of poly (maleic acid-styrene)-conjugated neocarzinostatin, SMANCS.
J. Takeshita
,
H. Maeda
,
R. Kanamaru
Gan
1982
Corpus ID: 29823586
The organ specificity and pharmacokinetics of SMANCS, poly (maleic acid-styrene)-conjugated neocarzinostatin (NCS), were…
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1982
1982
[Use of a lipid lymphographic agent, lipiodol, as a carrier of high molecular weight antitumor agent, smancs, for hepatocellular carcinoma].
T. Konno
,
H. Maeda
,
+9 authors
Y. Miyauchi
Gan to kagaku ryoho. Cancer & chemotherapy
1982
Corpus ID: 7133739
Two advantages of the present therapeutic approach were described. Firstly, a selective deposition of lipiodol in tumor tissue…
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