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poly(maleic acid-styrene)neocarzinostatin

Known as: SMANCS, copoly(styrene-maleic acid)neocarzinostatin, zinostatin stimalamer 
National Institutes of Health

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6 relations

Broader (4)

Antineoplastic AgentsMaleic AnhydridesPolystyrenesZinostatin

Narrower (1)

YM 881
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Pelioid‐type hepatocellular carcinoma with numerous eosinophilic infiltrations in a patient with primary biliary cirrhosis
A 65‐year‐old woman with liver injury was referred to our hospital in 1992. She was diagnosed with primary biliary cirrhosis (PBC… 
1998
1998
A novel dosage approach for evaluation of SMANCS [poly-(styrene-co-maleyl-half-n-butylate) - neocarzinostatin] in the treatment of primary hepatocellular carcinoma.
We report a Phase I/II clinical trial of poly-(styrene-co-maleyl-half-n-butylate)-neocarzinostatin (SMANCS) for intra-arterial… 
1990
1990
Comparison of the cytotoxic effects of the high- and low-molecular-weight anticancer agents on multidrug-resistant Chinese hamster ovary cells in vitro.
Neocarzinostatin (NCS), styrene-maleic acid copolymer-conjugated neocarzinostatin (SMANCS), and ricin exhibited cytotoxicity… 
1990
1990
Role of natural killer cells and macrophages in the nonspecific resistance to tumors in mice stimulated with SMANCS, a polymer-conjugated derivative of neocarzinostatin.
Copoly(styrene-maleic acid)-conjugated neocarzinostatin (SMANCS), a lipophilic derivative of the proteinaceous antitumor… 
1988
1988
Interferon induction by SMANCS: a polymer-conjugated derivative of neocarzinostatin.
Poly (styrene-co-maleic acid)-conjugated neocarzinostatin, SMANCS, induced antiviral activities in the circulation of mice. The… 
Highly Cited
1987
Highly Cited
1987
Binding to and internalization by cultured cells of neocarzinostatin and enhancement of its actions by conjugation with lipophilic styrene-maleic acid copolymer.
The binding of a copoly(styrene-maleic acid)-conjugated neocarzinostatin (NCS) designated as smancs (Mr 16,000), and parental NCS… 
1987
1987
Facilitated internalization of neocarzinostatin and its lipophilic polymer conjugate, SMANCS, into cytosol in acidic pH.
The effects of environmental pH on the binding and cytotoxicity of the antitumor proteins neocarzinostatin (NCS) and SMANCS… 
1987
1987
Tumor-targeted chemotherapy with lipid contrast medium and macromolecular anticancer drug (SMANCS) for renal cell carcinoma.
1982
1982
In vitro mode of action, pharmacokinetics, and organ specificity of poly (maleic acid-styrene)-conjugated neocarzinostatin, SMANCS.
The organ specificity and pharmacokinetics of SMANCS, poly (maleic acid-styrene)-conjugated neocarzinostatin (NCS), were… 
1982
1982
[Use of a lipid lymphographic agent, lipiodol, as a carrier of high molecular weight antitumor agent, smancs, for hepatocellular carcinoma].
Two advantages of the present therapeutic approach were described. Firstly, a selective deposition of lipiodol in tumor tissue… 
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