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pole plasm assembly

Establishment of the specialized cytoplasm found at the poles of the egg. An example of this is found in Drosophila melanogaster. [GOC:mtg_sensu]
National Institutes of Health

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pole plasm RNA localization

Papers overview

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2020
2020
Makorin 1 controls embryonic patterning by alleviating Bruno1-mediated repression of oskar translation
Makorins are evolutionary conserved proteins that contain C3H-type zinc finger modules and a RING E3 ubiquitin ligase domain. In… Expand
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2013
2013
Oskar Is Targeted for Degradation by the Sequential Action of Par-1, GSK-3, and the SCF-Slimb Ubiquitin Ligase
Translation of oskar messenger RNA (mRNA) is activated at the posterior of the Drosophila oocyte, producing Long Oskar, which… Expand
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2011
2011
A Role for Vasa in Regulating Mitotic Chromosome Condensation in Drosophila
Vasa (Vas) is a conserved DEAD-box RNA helicase expressed in germline cells that localizes to a characteristic perinuclear… Expand
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2011
2011
Oskar-induced endocytic activation and actin remodeling for anchorage of the Drosophila germ plasm.
In many animals, germ-cell fate is specified by inheritance of the germ plasm, which is enriched in maternal RNAs and proteins… Expand
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Highly Cited
2008
Highly Cited
2008
The endocytic pathway acts downstream of Oskar in Drosophila germ plasm assembly.
Cell fate is often determined by the intracellular localization of RNAs and proteins. In Drosophila oocytes, oskar (osk) RNA… Expand
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Highly Cited
2002
Highly Cited
2002
Kinesin I-dependent cortical exclusion restricts pole plasm to the oocyte posterior
Microtubules and the plus-end-directed microtubule motor Kinesin I are required for the selective accumulation of oskar mRNA at… Expand
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Highly Cited
2002
Highly Cited
2002
Oskar anchoring restricts pole plasm formation to the posterior of the Drosophila oocyte.
Localization of the maternal determinant Oskar at the posterior pole of Drosophila melanogaster oocyte provides the positional… Expand
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Highly Cited
2001
Highly Cited
2001
Barentsz is essential for the posterior localization of oskar mRNA and colocalizes with it to the posterior pole
The localization of Oskar at the posterior pole of the Drosophila oocyte induces the assembly of the pole plasm and therefore… Expand
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Highly Cited
1998
Highly Cited
1998
vasa is required for GURKEN accumulation in the oocyte, and is involved in oocyte differentiation and germline cyst development.
The Drosophila gene vasa is required for pole plasm assembly and function, and also for completion of oogenesis. To investigate… Expand
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Highly Cited
1994
Highly Cited
1994
Localization of vasa protein to the Drosophila pole plasm is independent of its RNA-binding and helicase activities.
The Drosophila gene vasa encodes a DEAD-box protein, which is localized during early oogenesis to the perinuclear region of the… Expand
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