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podosome assembly

The aggregation, arrangement and bonding together of a set of components to form a podosome, an actin-rich adhesion structure characterized by… Expand
National Institutes of Health

Related topics

Related topics

1 relation
negative regulation of podosome assembly

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Nrf2 Sequesters Keap1 Preventing Podosome Disassembly: A Quintessential Duet Moonlights in Endothelium.
AIMS Nrf2 (nuclear factor erythroid 2-like 2) is a transcription factor known to modulate blood vessel formation. Various… Expand
2016
2016
Impaired endothelial shear stress induces podosome assembly via VEGF up‐regulation
Podosomes are dynamic cytoskeletal membrane structures with local adhesive and proteolytic activity. They are critically involved… Expand
2015
2015
Fascin actin bundling controls podosome turnover and disassembly while cortactin is involved in podosome assembly by its SH3 domain in THP-1 macrophages and dendritic cells.
Podosomes are dynamic degrading devices present in myeloid cells among other cell types. They consist of an actin core with… Expand
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2015
2015
Tyrosine phosphorylation of WIP releases bound WASP and impairs podosome assembly in macrophages
ABSTRACT Podosomes are integrin-containing adhesion structures commonly found in migrating leukocytes of the monocytic lineage… Expand
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Review
2013
Review
2013
Podosomes in adhesion, migration, mechanosensing and matrix remodeling
Cells use various actin‐based motile structures to allow them to move across and through matrix of varying density and… Expand
Highly Cited
2012
Highly Cited
2012
Involvement of actin polymerization in podosome dynamics
Podosomes, which are formed by different monocyte derivatives, are small adhesion structures whose coordinated dynamics and… Expand
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2008
2008
A Novel Role for Calpain 4 in Podosome Assembly
 
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Highly Cited
2006
Highly Cited
2006
A signalling cascade involving PKC, Src and Cdc42 regulates podosome assembly in cultured endothelial cells in response to phorbol ester
The involvement of Src, Cdc42, RhoA and PKC in the regulation of podosome assembly has been identified in various cell models. In… Expand
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2004
2004
Polyphosphoinositides-dependent regulation of the osteoclast actin cytoskeleton and bone resorption
BackgroundGelsolin, an actin capping protein of osteoclast podosomes, has a unique function in regulating assembly and… Expand
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Highly Cited
2000
Highly Cited
2000
Gelsolin Deficiency Blocks Podosome Assembly and Produces Increased Bone Mass and Strength
Osteoclasts are unique cells that utilize podosomes instead of focal adhesions for matrix attachment and cytoskeletal remodeling… Expand
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