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platelet alpha granule

Known as: platelet alpha-granule 
A secretory organelle found in blood platelets, which is unique in that it exhibits further compartmentalization and acquires its protein content via… 
National Institutes of Health

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platelet alpha granule lumenplatelet alpha granule membrane

Papers overview

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2004
2004
Shift in the Balance between Circulating Thrombospondin-1 and Vascular Endothelial Growth Factor in Cancer Patients: Relationship to Platelet α-Granule Content and Primary Activation
Tumoral angiogenesis is regulated by the balance between factors that activate and inhibit angiogenesis. Elevated levels of… 
1994
1994
Effects of interleukin‐2 administration on platelet function in cancer patients
Platelet function in 16 patients with metastatlc renal cell carcinoma and melanoma was studied sequentially over the first 96 hr… 
1993
1993
Role of platelet membrane glycoproteins Ib/IX and IIb/IIIa, and of platelet alpha-granule proteins in platelet aggregation induced by human osteosarcoma cells.
We have previously shown that the platelet-aggregating activity of human MG-63 and HOS osteosarcoma cells depends at least in… 
1991
1991
Endogenous platelet fibrinogen surface expression on activated platelets.
Intracellular platelet fibrinogen surface expression was studied in arabinogalactan-purified, resting, and thrombin-stimulated… 
1990
1990
Platelet activation induces increased Fc gamma receptor expression.
Platelet contain Fc gamma RII. However, little is known about how the expression of these receptors is regulated. Inasmuch as… 
1989
1989
5‐day storage of single‐donor platelets obtained using a blood cell separator
Platelets were collected from normal donors via a blood cell separator (Fenwal CS‐3000). Platelets were stored initially in two… 
1988
1988
Evidence for an Increased Generation of Prostacyclin in the Microvasculature and an Impairment of the Platelet α-Granule Release in Chronic Renal Failure
Summary The formation of prostacyclin (PGI2) and thromboxane A2 and the release of beta-thromboglobulin (beta-TG) at the site of… 
1987
1987
Platelet acquired defect in PDGF and β thromboglobulin content in hairy cell leukaemia: improvement after interferon therapy
To investigate the platelet contribution to the development of myelofibrosis in hairy cell leukaemia (HCL), we have studied two… 
1985
1985
Metabolism of Sodium Pentosan Polysulphate in Man Measured by a New Competitive Binding Assay for Sulphated Polysaccharides – Comparison with Effects Upon Anticoagulant Activity, Lipolysis and…
Summary Three human volunteers were injected with a range of doses of pentosan polysulphate, SP54, i.v. or s.c. A competitive… 
Highly Cited
1984
Highly Cited
1984
Detection of Enhanced In Vivo Platelet α-Granule Release in Different Patient Groups - Comparison of β-Thromboglobulin, Platelet Factor 4 and Thrombospondin Assays
Summary During the platelet release reaction β-thromboglobulin (βTG), platelet factor 4 (PF4) and thrombospondin (TSP) are… 
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