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plasminogen activator activity

OBSOLETE. Catalysis of the specific cleavage of an Arg-Val bond in plasminogen to form plasmin. [EC:3.4.21.68, EC:3.4.21.73]
National Institutes of Health

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Related topics

8 relations
AnistreplasePLAT protein, humanPlasminogen ActivatorReteplase
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Papers overview

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Highly Cited
1999
Highly Cited
1999
Moderate alcohol intake and lower risk of coronary heart disease: meta-analysis of effects on lipids and haemostatic factors
Abstract Objective: To summarise quantitatively the association between moderate alcohol intake and biological markers of risk of… Expand
Highly Cited
1995
Highly Cited
1995
Plasminogen activator and plasminogen activator inhibitor I release during experimental endotoxaemia in chimpanzees: effect of interventions in the cytokine and coagulation cascades.
1. Disseminated intravascular coagulation frequently accompanies Gram-negative sepsis and may contribute to widespread deposition… Expand
Highly Cited
1994
Highly Cited
1994
Inhibition of endotoxin-induced activation of coagulation and fibrinolysis by pentoxifylline or by a monoclonal anti-tissue factor antibody in chimpanzees.
Knowledge of the pathogenetic mechanisms responsible for the activation of the coagulation system associated with endotoxemia is… Expand
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Highly Cited
1993
Highly Cited
1993
Mechanism of action of angiostatic steroids: Suppression of plasminogen activator activity via stimulation of plasminogen activator inhibitor synthesis
Recently, a novel class of angiostatic steroids which block angiogenesis in several systems has been described. Since the… Expand
Highly Cited
1991
Highly Cited
1991
Lipoprotein (a) regulates plasminogen activator inhibitor-1 expression in endothelial cells. A potential mechanism in thrombogenesis.
Lipoprotein (a) (Lp(a)) is a low density lipoprotein-like particle which contains the plasminogen-like apolipoprotein a. Lp(a… Expand
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Highly Cited
1986
Highly Cited
1986
Autonomous functions of structural domains on human tissue-type plasminogen activator.
Transfected mouse Ltk- cells were employed for transient expression of recombinant human tissue-type plasminogen activator (t-PA… Expand
Highly Cited
1984
Highly Cited
1984
Purification of an inhibitor of plasminogen activator (antiactivator) synthesized by endothelial cells.
Cultured bovine aortic endothelial cells are associated with an unusually stable fibrinolytic inhibitor (Loskutoff, D.J., van… Expand
Highly Cited
1984
Highly Cited
1984
Bioactivities, estrogen receptor interactions, and plasminogen activator-inducing activities of tamoxifen and hydroxy-tamoxifen isomers in MCF-7 human breast cancer cells.
Tamoxifen is used widely in the treatment of endocrine-responsive breast cancers in humans. Studies were undertaken to examine… Expand
Highly Cited
1981
Highly Cited
1981
Immunological characterization of plasminogen activator activities in human tissues and body fluids.
Human plasminogen activators were compared immunologically in both a double-diffusion technique and quenching experiments on the… Expand
Highly Cited
1980
Highly Cited
1980
Relationship between tissue plasminogen activator and the activators in blood and vascular wall.
Abstract To explore the relation between tissue plasminogen activator and both vascular and blood fibrinolytic activity, an… Expand
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