plasminogen activation

Known as: cleavage of plasminogen to plasmin 
The process in which inactive plasminogen is processed to active plasmin. This process includes cleavage at an internal Arg-Val site to form an N… (More)
National Institutes of Health

Papers overview

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Review
2000
Review
2000
Generation of the serine proteinase plasmin from the extracellular zymogen plasminogen can be catalyzed by either of two other… (More)
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Review
2000
Review
2000
Plasminogen activator inhibitor type 1 is a potential target in renal fibrogenesis. The progression of renal lesions to fibrosis… (More)
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Review
2000
Review
2000
Plasminogen activation is a key event in the fibrinolytic system that results in the dissolution of blood clots, and also… (More)
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Highly Cited
1998
Highly Cited
1998
TAFI (thrombin-activable fibrinolysis inhibitor) is a recently described plasma zymogen that, when exposed to the thrombin… (More)
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Highly Cited
1995
Highly Cited
1995
The urokinase plasminogen activator receptor (uPAR), a glycosylphosphatidylinositol-linked glycoprotein, plays a central role in… (More)
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Highly Cited
1994
Highly Cited
1994
In the preceding paper (Hajjar, K. A., Jacovina, A. T., and Chacko, J. (1994) J. Biol. Chem. 269, 21191-21197), we identified a M… (More)
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Highly Cited
1993
Highly Cited
1993
Amphoterin is a heparin-binding protein that is developmentally regulated in brain and functionally involved in neurite outgrowth… (More)
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Highly Cited
1991
Highly Cited
1991
Plasminogen binding to cell surfaces results in enhanced plasminogen activation, localization of the proteolytic activity of… (More)
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Highly Cited
1990
Highly Cited
1990
The surface receptor for urokinase plasminogen activator (uPAR) has been recognized in recent years as a key molecule in… (More)
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Highly Cited
1989
Highly Cited
1989
The binding of urokinase-type plasminogen activators (u-PA) to receptors on various cell types has been proposed to be an… (More)
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