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plasmepsin

Known as: plasmepsin protease, aspartic hemoglobinase, Plasmodium aspartic proteinase G 
 
National Institutes of Health

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Highly Cited
2017
Highly Cited
2017
BACKGROUND As the prevalence of artemisinin-resistant Plasmodium falciparum malaria increases in the Greater Mekong subregion… Expand
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Highly Cited
2015
Highly Cited
2015
Plasmepsin V, an essential aspartyl protease of malaria parasites, has a key role in the export of effector proteins to parasite… Expand
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Highly Cited
2014
Highly Cited
2014
A small molecule inhibitor of the malarial protease Plasmepsin V impairs protein export and cellular remodeling, reducing… Expand
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Highly Cited
2013
Highly Cited
2013
Plasmodium falciparum exports several hundred effector proteins that remodel the host erythrocyte and enable parasites to acquire… Expand
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Highly Cited
2010
Highly Cited
2010
During their intraerythrocytic development, malaria parasites export hundreds of proteins to remodel their host cell. Nutrient… Expand
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Highly Cited
2010
Highly Cited
2010
Plasmodium falciparum causes the virulent form of malaria and disease manifestations are linked to growth inside infected… Expand
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Highly Cited
2008
Highly Cited
2008
Intraerythrocytic malaria parasites use host hemoglobin as a major nutrient source. Aspartic proteases (plasmepsins) and cysteine… Expand
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Highly Cited
2005
Highly Cited
2005
Aspartic proteases participate in a wide variety of cellular processes in eukaryotic organisms. The genome of the human malaria… Expand
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1997
1997
Two aspartic proteinases, plasmepsins I and II, are present in the digestive vacuole of the human malarial parasite Plasmodium… Expand
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Highly Cited
1994
Highly Cited
1994
The human malaria parasite, Plasmodium falciparum, degrades nearly all its host cell hemoglobin during a short segment of its… Expand
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