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pivaloylcarnitine
Known as:
pivaloyl carnitine
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (1)
Carnitine
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Stable-isotope dilution measurement of isovalerylglycine by tandem mass spectrometry in newborn screening for isovaleric acidemia.
Y. Shigematsu
,
I. Hata
,
Yukie Tanaka
Clinica chimica acta; international journal of…
2007
Corpus ID: 38392675
2006
2006
Involvement of Recognition and Interaction of Carnitine Transporter in the Decrease of l-Carnitine Concentration Induced by Pivalic Acid and Valproic Acid
N. Okamura
,
Shuichi Ohnishi
,
Hiroyuki Shimaoka
,
R. Norikura
,
H. Hasegawa
Pharmaceutical Research
2006
Corpus ID: 23303955
PurposeProdrugs with pivalic acid and valproic acid decrease l-carnitine concentration in plasma and tissues by urinary excretion…
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Review
2006
Review
2006
Hypocarnitinaemia Induced by Sodium Pivalate in the Rat is Associated with Left Ventricular Dysfunction and Impaired Energy Metabolism
T. Broderick
Drugs in R&D
2006
Corpus ID: 20639503
Carnitine is a naturally occurring compound that is essential in energy metabolism of the mammalian heart. In addition to its…
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2006
2006
Possible mechanism for species difference on the toxicity of pivalic acid between dogs and rats.
Toshiro Yamaguchi
,
Y. Nakajima
,
Yutaka Nakamura
Toxicology and Applied Pharmacology
2006
Corpus ID: 24169997
2001
2001
Up-Regulation of Carnitine Transporters Helps Maintain Tissue Carnitine Levels in Carnitine Deficiency Induced by Pivalic Acid
N. Okudaira
,
M. Fujigaki
,
T. Nakayoshi
,
I. Komiya
,
Y. Sugiyama
Pharmaceutical Research
2001
Corpus ID: 12054410
AbstractPurpose. Pivalic acid (PVA) forms conjugates with endogenous carnitine and enhances its excretion. The purpose of this…
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1993
1993
Preferential elimination of pivalate with supplemental carnitine via formation of pivaloylcarnitine in man.
B. Melegh
,
B. Sumegi
,
A. Sherry
Xenobiotica; the fate of foreign compounds in…
1993
Corpus ID: 2209601
1. To evaluate the effectiveness of carnitine administration in aiding the elimination of pivalate liberated from pivampicillin…
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1993
1993
Properties of the medium chain/long chain carnitine acyltransferase purified from rat liver microsomes.
C. Chung
,
L. Bieber
Journal of Biological Chemistry
1993
Corpus ID: 29552919
1992
1992
Determination of pivaloylcarnitine in human plasma and urine by high-performance liquid chromatography with fluorescence detection.
M. Konishi
,
H. Hashimoto
Journal of Pharmacy and Science
1992
Corpus ID: 7471371
A high-performance liquid chromatographic (HPLC) method was developed for the determination of pivaloylcarnitine, one of the…
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1992
1992
Phase I clinical studies of S-1108: safety and pharmacokinetics in a multiple-administration study with special emphasis on the influence on carnitine body stores
M. Nakashima
,
Toshihiko Uematsu
,
+4 authors
S. Yamamoto
Antimicrobial Agents and Chemotherapy
1992
Corpus ID: 38175692
S-1108, the prodrug of S-1006, was given to healthy volunteers three times a day (TID) for 8 days in a dose of 200 mg in a…
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1985
1985
Carnitine and glucuronic acid conjugates of pivalic acid.
S. Vickers
,
C. Duncan
,
+5 authors
B. Arison
Xenobiotica; the fate of foreign compounds in…
1985
Corpus ID: 23442430
The [1-14C]pivaloyloxyethyl ester of methyldopa administered to man and cynomolgus monkeys resulted in the elimination in the…
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