pitrakinra

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2007-2016
012320072016

Papers overview

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2017
2017
Ulcerative colitis (UC) is a highly progressive inflammatory disease that requires the interaction of epithelial, immune… (More)
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2016
2016
Animal models reflective of ulcerative colitis (UC) remain a major challenge, and yet are crucial to understand mechanisms… (More)
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2013
2013
  • Pharmaceutical Medicine
  • 2013
Given the very high prevalence of asthma globally— approximately 300 million people according to recent World Health Organization… (More)
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2012
2012
Animal models of human inflammatory diseases have limited predictive quality for human clinical trials for various reasons… (More)
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2012
2012
BACKGROUND This is the first large pharmacogenetic investigation of the inflammatory IL-4/IL-13 pathway in patients with moderate… (More)
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Review
2012
Review
2012
Aeroallergens are the most common triggers for the development of asthma. Recent birth cohort studies have identified viral… (More)
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2010
2010
In asthma, airway inflammation is driven by Th2-related cytokines, such as IL-4, IL-5 and IL-13. IL-4 and IL-13, in particular… (More)
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2010
2010
BACKGROUND Pitrakinra is a recombinant protein derived from human interleukin-4 (IL-4) that binds to IL-4Ralpha and acts as a… (More)
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Review
2010
Review
2010
IMPORTANCE OF THE FIELD In asthma IL-4 and IL-13 have been demonstrated to play major pathogenic roles and therefore their… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Increases in T helper (Th) 2 cytokine concentrations have been seen in atopic asthma, with interleukin 4 and… (More)
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