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pirazolac
Known as:
4-(4-chlorophenyl)-1-(4-fluorophenyl)pyrazole-3-acetic acid
National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
Pyrazoles
Papers overview
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2010
2010
Pharmacokinetics of pirazolac — A new anti-inflammatory drug — in human volunteers I. Absorption, disposition, biotransformation and excretion
U. Tauber
,
C. Weiss
,
W. Krause
,
B. Acksteiner
,
H. Matthes
European journal of drug metabolism and…
2010
Corpus ID: 27119903
SummaryThe absorption, disposition, biotransformation and excretion of the nonsteroidal anti-inflammatory drug pirazolac were…
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2004
2004
Transsynovial distribution and protein binding of pirazolac in patients with rheumatoid arthritis
M. Kurowski
,
A. Dunky
,
M. Geddawi
European Journal of Clinical Pharmacology
2004
Corpus ID: 35023694
SummaryFollowing a washout period of 7 days, twenty-one patients suffering from rheumatoid arthritis and 3 from osteo-arthritis…
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1990
1990
A 12-week double-blind study of the efficacy, safety and tolerance of pirazolac b.i.d. compared with indomethacin t.i.d. in patients with ankylosing spondylitis.
Carlo Carcassi
,
G. Nasa
,
G. Perpignano
Drugs under experimental and clinical research
1990
Corpus ID: 2251252
A 12-week trial was carried out to compare the efficacy of pirazolac (300-600 mg b.i.d.) with that of indomethacin (25-50 mg t.i…
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1990
1990
The pharmacokinetics of pirazolac in human subjects.
U. Täuber
Drugs under experimental and clinical research
1990
Corpus ID: 44969991
Pirazolac (PAA) is a new non-steroidal anti-inflammatory drug (NSAID) belonging to the subgroup of heterocyclic acetic acids. PAA…
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1990
1990
Multicentre double-blind study of the efficacy, safety and tolerance of pirazolac compared with sulindac in patients with rheumatoid arthritis.
R. Numo
Drugs under experimental and clinical research
1990
Corpus ID: 811660
Of the 160 patients (80 pirazolac/80 sulindac) who entered the study through 14 investigators, three-quarters completed a 12…
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1990
1990
Neutrophil functional and arachidonic acid metabolic correlates and clinical disease activity in pirazolac-treated rheumatoid arthritis patients.
R. Turner
,
J. Johnson
,
S. R. Turner
,
M. Mcgee
,
F. Kashanian
Drugs under experimental and clinical research
1990
Corpus ID: 22298871
Neutrophils from 20 medication-free rheumatoid arthritis patients were chemotactically hyporesponsive to 2 x 10(-8) M formyl…
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1987
1987
Effects of pirazolac on arachidonic acid metabolism in the human synovial system.
M. Kurowski
,
A. Dunky
,
M. Geddawi
Current Medical Research and Opinion
1987
Corpus ID: 44930837
Six patients suffering from rheumatoid arthritis with massive knee joint effusions were treated with single daily doses of 600 mg…
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1985
1985
Pharmacokinetics of Pirazolac – a New Anti-Inflammatory Drug – in Human Volunteers II. Dose Linearity of Plasma Levels and Excretion
U. Täuber
,
C. Weiss
,
H. Matthes
Pharmaceutical Research
1985
Corpus ID: 2547354
The concentration-time course of pirazolac in plasma and its urinary excretion were investigated in 6 young volunteers (3 males…
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1985
1985
Differential dosing study of pirazolac, a new non-steroidal anti-inflammatory agent, in patients with rheumatoid arthritis.
D. Symmons
,
B. Clark
,
G. Panayi
,
M. Geddawi
Current Medical Research and Opinion
1985
Corpus ID: 32211120
Twenty-four patients with classical or definite rheumatoid arthritis participated in a 4-week double-blind crossover study to…
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1985
1985
Comparison of occult blood loss caused by pirazolac and diclofenac sodium: a double-blind crossover study.
R. Bown
,
B. Martin
,
M. Geddawi
Current Medical Research and Opinion
1985
Corpus ID: 30688777
A study was carried out in 10 healthy subjects to compare the faecal blood loss caused by pirazolac, a new non-steroidal anti…
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