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piperidine-4-carboxamide

 
National Institutes of Health

Papers overview

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2015
2015
We report the design, synthesis and binding evaluation against σ1 and σ2 receptors of a series of new piperidine-4-carboxamide… Expand
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2015
2015
Present work comprises of synthesis of sulfonamide and amide derivatives of piperidine-4-carboxamide via amino–dechlorination and… Expand
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2014
2014
Based on a putative 'Y shape' pharmacophore model of CCR5 inhibitors, a series of novel piperidine-4-carboxamide derivatives were… Expand
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2013
2013
1. (S) -4-amino-N- (1- (4-chlorophenyl) -3-hydroxypropyl) -1- (7H-pyrrolo [2,3-d] pyrimidin-4-yl) piperidin-4- carboxamide (m. e… Expand
2010
2010
In this study, we have developed QSAR models for a series of 38 piperidine-4-carboxamide CCR5 antagonists using CoMFA, CoMSIA and… Expand
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Highly Cited
2006
Highly Cited
2006
We incorporated various polar groups into previously described piperidine-4-carboxamide CCR5 antagonists to improve their… Expand
2005
2005
Replacement of the 5-oxopyrrolidin-3-yl fragment in the previously reported lead structure with a 1-acetylpiperidin-4-yl group… Expand