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piperaquine

Known as: Piperaquinoline, Quinoline, 4,4'-(1,3-Propanediyldi-4,1-Piperazinediyl)Bis(7-Chloro)-, 1,3-bis(1-(7-chloro-4'-quinolyl)-4'-piperazinyl)propane 
 
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
BACKGROUND As the prevalence of artemisinin-resistant Plasmodium falciparum malaria increases in the Greater Mekong subregion… Expand
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Highly Cited
2016
Highly Cited
2016
BACKGROUND Artemisinin resistance in Plasmodium falciparum threatens to reduce the efficacy of artemisinin combination therapies… Expand
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Highly Cited
2015
Highly Cited
2015
ABSTRACT Western Cambodia is recognized as the epicenter of Plasmodium falciparum multidrug resistance. Recent reports of the… Expand
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Highly Cited
2015
Highly Cited
2015
BACKGROUND Dihydroartemisinin-piperaquine has been adopted as first-line artemisinin combination therapy (ACT) for multidrug… Expand
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Highly Cited
2014
Highly Cited
2014
This letter suggests that rising treatment failures and parasite clearance times and decreasing piperaquine sensitivity 3 years… Expand
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Highly Cited
2012
Highly Cited
2012
ABSTRACT We describe here the results of antimalarial therapeutic efficacy studies conducted in Cambodia from 2008 to 2010. A… Expand
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Highly Cited
2009
Highly Cited
2009
Background Artemisinin combination therapies (ACTs) are currently the preferred option for treating uncomplicated malaria… Expand
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Highly Cited
2009
Highly Cited
2009
ABSTRACT We have analyzed the in vitro chemosensitivity profiles of 115 Kenyan isolates for chloroquine (CQ), piperaquine… Expand
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Review
2005
Review
2005
Piperaquine is a bisquinoline antimalarial drug that was first synthesised in the 1960s, and used extensively in China and… Expand
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Southeast Asia has the most resistant malaria parasites in the world, which severely limits treatment options. There… Expand
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