pioglitazone

Known as: Pioglitazonum, (+-)-5-((4-(2-(5-Ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione, Pioglitazona 
An orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity. Pioglitazone activates peroxisome proliferator… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
OBJECTIVE The association between pioglitazone and bladder cancer has not been investigated in Asians. We aimed to investigate… (More)
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Highly Cited
2011
Highly Cited
2011
OBJECTIVE Some preclinical in vivo studies and limited human data suggest a possible increased risk of bladder cancer with… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Impaired glucose tolerance is associated with increased rates of cardiovascular disease and conversion to type 2… (More)
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Highly Cited
2008
Highly Cited
2008
CONTEXT No antidiabetic regimen has demonstrated the ability to reduce progression of coronary atherosclerosis. Commonly used… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND & AIMS Nonalcoholic steatohepatitis (NASH) is a leading cause of chronic liver disease for which there is limited… (More)
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Highly Cited
2007
Highly Cited
2007
CONTEXT Pioglitazone is widely used for glycemic control in patients with type 2 diabetes mellitus, but evidence is mixed… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Patients with type 2 diabetes are at high risk of fatal and non-fatal myocardial infarction and stroke. There is… (More)
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Highly Cited
2005
Highly Cited
2005
Thiazolidenediones such as pioglitazone improve insulin sensitivity in diabetic patients by several mechanisms, including… (More)
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Highly Cited
2004
Highly Cited
2004
Nonalcoholic steatohepatitis (NASH) is a common chronic liver disease for which there is no known effective therapy. A proportion… (More)
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Highly Cited
2002
Highly Cited
2002
We examined the effect of pioglitazone on abdominal fat distribution to elucidate the mechanisms via which pioglitazone improves… (More)
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