Skip to search formSkip to main contentSkip to account menu

pioglitazone

Known as: Pioglitazonum, (+-)-5-((4-(2-(5-Ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione, Pioglitazona 
An orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity. Pioglitazone activates peroxisome proliferator… 
National Institutes of Health

Related topics

Related topics

25 relations

Narrower (4)

AD 4833ActosOseniPioglitazone hydrochloride
Diabetes Mellitus, Non-Insulin-DependentDrug AllergyLiver diseasesMetformin hydrochloride 500 MG / pioglitazone 15 MG Oral Tablet

Broader (2)

Hypoglycemic AgentsThiazolidinediones

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
A protocol for active surveillance of acute myocardial infarction in association with the use of a new antidiabetic pharmaceutical agent
To describe a protocol for active surveillance of acute myocardial infarction (AMI) in users of a recently approved oral… 
Highly Cited
2008
Highly Cited
2008
No significant effect of SLCO1B1 polymorphism on the pharmacokinetics of rosiglitazone and pioglitazone.
AIMS To examine possible effects of polymorphism in the SLCO1B1 gene, encoding the hepatic uptake transporter organic anion… 
Highly Cited
2007
Highly Cited
2007
Pioglitazone Inhibits In-Stent Restenosis in Atherosclerotic Rabbits by Targeting Transforming Growth Factor-&bgr; and MCP-1
Objective—Although emerging data from preclinical and clinical studies suggests a reduction of in-stent restenosis with… 
2007
2007
Wnt-signaling is maintained and adipogenesis inhibited by TNFalpha but not MCP-1 and resistin.
2006
2006
PPAR‐γ expression in pituitary tumours and the functional activity of the glitazones: evidence that any anti‐proliferative effect of the glitazones is independent of the PPAR‐γ receptor
Objective   It has been reported that both normal pituitary and pituitary tumours express PPAR‐γ, a nuclear hormone receptor, the… 
Highly Cited
2004
Highly Cited
2004
Inhibitory effect of pioglitazone on expression of adhesion molecules on neutrophils and endothelial cells
The interaction between leukocytes and the vascular endothelial cells (EC) via cellular adhesion molecules plays an important… 
Highly Cited
1999
Highly Cited
1999
Pharmacological profiles of a novel oral antidiabetic agent, JTT-501, an isoxazolidinedione derivative.
Highly Cited
1996
Highly Cited
1996
Effect of pioglitazone on vascular reactivity in vivo and in vitro.
Pioglitazone (a thiazolidinedione derivative) increases insulin sensitivity and prevents hypertension in the Dahl-salt-sensitive… 
Highly Cited
1996
Highly Cited
1996
Pioglitazone improves insulin signaling defects in skeletal muscle from Wistar fatty (fa/fa) rats.
The effects of pioglitazone, a novel antidiabetic insulin-sensitizing agent, on insulin signaling in skeletal muscles from… 
Highly Cited
1994
Highly Cited
1994
Potentiation of insulin stimulation of phosphatidylinositol 3-kinase by thiazolidinedione-derived antidiabetic agents in Chinese hamster ovary cells expressing human insulin receptors and L6 myotubes…
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)