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picotamide

Known as: 4-methoxy-N,N'-bis(3-pyridinylmethyl)-1,3-benzenedicarboxamide 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

Phthalic AcidsPlatelet Aggregation Inhibitors

Papers overview

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2003
2003
Effects of picotamide, an antiplatelet agent, on cardiovascular, events in 438 claudicant patients with diabetes: a retrospective analysis of the ADEP study.
Picotamide is an antiplatelet drug which inhibits thromboxane A2 (TxA2) synthase and antagonizes TxA2 receptors. In the ADEP… 
2002
2002
Evaluation of the effects of anti-thromboxane agents in platelet-vessel wall interaction.
1999
1999
Assessment of Occlusion of the Vascular Access in Patients on Chronic Hemodialysis: Comparison of Physical Examination with Continuous-Wave Doppler Ultrasound
Background: Dialysis access occlusion is the most common cause of hospitalization and a frequent indirect cause of mortality in… 
1998
1998
Long-Term Safety and Efficacy of Picotamide, a Dual-Action Antithromboxane Agent, in Diabetic Patients with Carotid Atherosclerosis: A 6-Year Follow-Up Study
In a controlled, randomized, 6-year trial the safety and efficacy of picotamide, a dual-action antithromboxane agent, were… 
1997
1997
The effects of thromboxane A2 inhibition (Picotamide) and angiotensin II receptor blockade (Losartan) in primary Raynaud's phenomenon
Pancera P, Sansone S, Secchi S, Covi G, Lechi A (University of Verona, Verona, Italy). The effects of thromboxane A2 inhibition… 
1996
1996
Picotamide inhibition of excess in vitro thromboxane B2 release by colorectal mucosa in inflammatory bowel disease.
BACKGROUND: Inflammatory bowel disease is associated with increased mucosal release of eicosanoids. Among these, thromboxane A2… 
1995
1995
Effects of picotamide, an antithromboxane agent, on carotid atherosclerotic evolution. A two-year, double-blind, placebo-controlled study in diabetic patients.
BACKGROUND AND PURPOSE We assessed the effects of long-term treatment with picotamide, an antiplatelet agent with dual… 
1994
1994
Binding kinetics and antiplatelet activities of picotamide, a thromboxane A2 receptor antagonist
1 Picotamide was shown to inhibit platelet binding of thromboxane A2 (TxA2)‐mimetics and to cause a reduction of TxA2 platelet… 
1994
1994
The role of extraplatelet thromboxane A2 in unstable angina investigated with a dual thromboxane A2 inhibitor: importance of activated monocytes
BackgroundThe role of thromboxane A2 (TxA2) in unstable angina has not yet been defined. TxA2 receptor antagonists may be of… 
1993
1993
Picotamide, a Dual TXB Synthetase Inhibitor and TXB Receptor Antagonist, Reduces Exercise-Induced Albuminuria in Microalbuminuric Patients With NIDDM
We investigated the short-term effect of the TXB inhibitor picotamide on albuminuria induced by exercise in 15 microalbuminuric… 
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