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photoreceptor cell fate determination

The process in which a cell becomes capable of differentiating autonomously into a photoreceptor cell regardless of its environment; upon… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Knockout of Nr2e3 prevents rod photoreceptor differentiation and leads to selective L-/M-cone photoreceptor degeneration in zebrafish.
Mutations in the photoreceptor cell-specific nuclear receptor gene Nr2e3 increased the number of S-cone photoreceptors in human… Expand
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Highly Cited
2011
Highly Cited
2011
An Essential Role for RAX Homeoprotein and NOTCH–HES Signaling in Otx2 Expression in Embryonic Retinal Photoreceptor Cell Fate Determination
The molecular mechanisms underlying cell fate determination from common progenitors in the vertebrate CNS remain elusive. We… Expand
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2011
2011
Excess cones in the retinal degeneration rd7 mouse, caused by the loss of function of orphan nuclear receptor Nr2e3, originate from early-born photoreceptor precursors.
The orphan nuclear receptor NR2E3 is a direct transcriptional target of NRL, the key basic motif leucine zipper transcription… Expand
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Review
2010
Review
2010
Transcriptional regulation of photoreceptor development and homeostasis in the mammalian retina
In the developing vertebrate retina, diverse neuronal subtypes originate from multipotent progenitors in a conserved order and… Expand
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Highly Cited
2010
Highly Cited
2010
Blimp1 Suppresses Chx10 Expression in Differentiating Retinal Photoreceptor Precursors to Ensure Proper Photoreceptor Development
The zinc finger transcription factor Blimp1 plays fundamentally important roles in many cell lineages and in the early… Expand
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2009
2009
Regulation of photoreceptor precursor differentiation in retinal development
s S91 as NSCs cells surface molecules, were recognized by E-PHA. However, lectin blot analysis revealed that E-PHA bound to… Expand
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Highly Cited
2007
Highly Cited
2007
Functional roles of Otx2 transcription factor in postnatal mouse retinal development.
We previously reported that Otx2 is essential for photoreceptor cell fate determination; however, the functional role of Otx2 in… Expand
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2006
2006
Retinoic Acid Regulates the Expression of Photoreceptor Transcription Factor NRL*
NRL (neural retina leucine zipper) is a key basic motif-leucine zipper (bZIP) transcription factor, which orchestrates rod… Expand
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Review
2005
Review
2005
[Mechanisms of retinal photoreceptor cell fate determination].
PURPOSE Understanding the molecular mechanisms by which distinct cell fate is determined during organogenesis is a central issue… Expand
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Highly Cited
2003
Highly Cited
2003
Otx2 homeobox gene controls retinal photoreceptor cell fate and pineal gland development
Understanding the molecular mechanisms by which distinct cell fate is determined during organogenesis is a central issue in… Expand
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