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The small protein Bv8, isolated from the amphibian skin, belongs to a novel family of secreted proteins linked to several… Expand A recent study from our laboratory indicated additional tissue injury during rewarming of a cooled rabbit leg. Oxygen-derived… Expand The phospholipase inhibitor mepacrine has been shown to delay cell death of metabolically inhibited cultured cardiomyocytes. The… Expand The effects of the inhibition of phospholipid degradation and superoxide radical generation on prostaglandin synthesis associated… Expand Manoalide, an unusual nonsteroidal sesterterpenoid recently isolated from sponge, antagonizes phorbol-induced inflammation but… Expand We have examined the effect of activated neutrophils on the release of prostacyclin (PGI2) from cultured endothelial cells by… Expand The biochemical events that lead to bradykinin stimulation of cAMP accumulation in human fibroblasts were examined. Treatment of… Expand 1 Leukotriene C4 (LTC4), LTD4, slow‐reacting substance of anaphylaxis (SRS‐A) (from guinea‐pig lung), bradykinin (Bk) and… Expand : Feverfew has been used since antiquity to treat fevers and other inflammatory conditions. Feverfew extracts were found to… Expand We have examined whether inhibition by mepacrine or freeing of arachidonic acid from platelet phospholipids inhibits platelet… Expand